Drug-Induced Alopecia

    May 1999 in “ PubMed
    Patricia M. L. A. van den Bemt, C. C. E. Brodie‐Meijer, R. M. A. Krijnen, C. Nieboer
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    TLDR Some medications can cause reversible hair loss by affecting hair growth cycles.
    The document from 1999 discussed drug-induced alopecia, a condition where hair loss is caused by certain medications. Hair follicles go through cycles of growth (anagen phase), transition (catagen phase), and rest (telogen phase), and losing more than 120 hairs daily is classified as alopecia. Drugs can cause a diffuse, reversible alopecia by influencing these cycles. However, establishing a causal relationship between a suspected drug and hair loss can be challenging due to the many potential causes of hair loss. The main categories of drugs that may cause alopecia, as listed in the literature, include cytostatics, anticoagulants, interferons, tretinoid derivatives, and lithium carbonate. The Netherlands Pharmacovigilance Foundation LAREB reported alopecia as a side effect of antimalarials, beta-receptor blocking agents, sex hormones, ACE inhibitors, angiotensin II antagonists, and anticoagulants.
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