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Glossary Angiotensin-Converting Enzyme 2

regulates blood pressure and is a SARS-CoV-2 entry point

Angiotensin-Converting Enzyme 2 (ACE2) is a protein found on the surface of many cell types, including those in the lungs, heart, and kidneys. It plays a crucial role in regulating blood pressure by converting angiotensin II, a molecule that can increase blood pressure, into angiotensin 1-7, which has the opposite effect. ACE2 is also known for being the entry point for the SARS-CoV-2 virus, which causes COVID-19, making it a significant focus of medical research.

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research The Impact of Angiotensin-Converting Enzyme 2 (ACE2) Expression Levels in Patients with Comorbidities on COVID-19 Severity: A Comprehensive Review

52 citations , August 2021 in “Microorganisms”

This review observes higher ACE2 expression in myocardial and lung tissues of heart failure and COPD patients but finds no link between RAAS inhibitors and COVID-19 severity.

research ACE2 Inhibits Dermal Regeneration Through Ang II in Tissue Expansion

1 citations , January 2025 in “Journal of Cosmetic Dermatology”

This study found that increased ACE2 expression, prompted by mechanical stretch, promotes skin regeneration and reduces dermal thinning during tissue expansion by enhancing collagen synthesis, suggesting ACE2's potential to improve clinical outcomes in reconstructive surgery settings.

research Lisinopril-Induced Alopecia: A Case Report

8 citations , June 2016 in “Journal of Pharmacy Practice”

This case report suggests that lisinopril may cause alopecia, which resolved after the patient switched to losartan potassium.

research [Drug induced alopecia].

4 citations , May 1999 in “PubMed”

This article reviews various drugs reported to cause alopecia, including cytostatics and anticoagulants, but does not present new research results; it suggests that drug-related hair loss can be difficult to prove.

research Culprits of Medication-Induced Telogen Effluvium, Part 2

January 2024 in “Cutis”

This review discusses anticoagulant and antihypertensive medications as potential contributors to medication-induced telogen effluvium and reports no new clinical results.

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community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Vasodilators, Min, L-arginine, Niacin, Lisinoprol, etc.

in Minoxidil 4 upvotes 3 years ago

The conversation discusses the use of vasodilators like Minoxidil, L-arginine, and Niacin for hair regrowth, with Minoxidil causing intolerable side effects for the original poster. It also highlights that certain medications, including Lisinopril, antidepressants, and statins, can cause hair loss.

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