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GlossaryAngiotensin-Converting Enzyme

regulates blood pressure by converting angiotensin I to angiotensin II

Angiotensin-Converting Enzyme (ACE) is a protein that plays a crucial role in regulating blood pressure by converting angiotensin I, an inactive hormone, into angiotensin II, a potent vasoconstrictor that narrows blood vessels and increases blood pressure. ACE inhibitors are commonly used medications to treat high blood pressure and heart failure by blocking this enzyme's activity, thereby relaxing blood vessels and lowering blood pressure.

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research Association Between Angiotensin-Converting Enzyme Gene Insertion Deletion Polymorphism and Androgenetic Alopecia Susceptibility Among Egyptian Patients: A Preliminary Case-Controlled Study

1 citations , September 2021 in “Journal of Cosmetic Dermatology”

Certain gene variations may increase the risk of hair loss in Egyptians.

Increased Frequency of the DI Genotype of the Angiotensin-I Converting Enzyme and Association of the II Genotype with Insulin Resistance in Polycystic Ovary Syndrome

research Increased Frequency of the DI Genotype of the Angiotensin-I Converting Enzyme and Association of the II Genotype with Insulin Resistance in Polycystic Ovary Syndrome

16 citations , January 2012 in “European Journal of Endocrinology”

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

research The Impact of Angiotensin-Converting Enzyme 2 (ACE2) Expression Levels in Patients with Comorbidities on COVID-19 Severity: A Comprehensive Review

52 citations , August 2021 in “Microorganisms”

Higher ACE2 levels in certain tissues may worsen COVID-19 in people with other health issues, especially older adults.

research Studying the Correlation of Renin-Angiotensin-System Components and Insulin Resistance in Polycystic Ovary Syndrome

12 citations , March 2013 in “Gynecological Endocrinology”

The study found a significant link between the renin-angiotensin system and insulin resistance in women with polycystic ovary syndrome.

research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

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community 11 months on 5mg oral minoxidil

in Progress Pictures 976 upvotes 2 years ago

A user's 11-month progress using 5mg oral minoxidil for hair loss. The user reported significant hair regrowth, including on the beard and eyebrows, and experienced minor side effects like headaches and increased body hair.

community Fats on your Head to Stop Hair Loss?

in Research/Science 143 upvotes 1 year ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community Using Antihypertensive drugs for hair loss

in Chat 6 upvotes 3 years ago

The conversation discusses the potential connection between baldness, heart disease, and high blood pressure. Treatments mentioned include Minoxidil, Spironolactone, and Finasteride.

community P-1075: a BETTER version of Minoxidil

in Research/Science 1 month ago

P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.

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