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GlossaryAngiotensin-Converting Enzyme

regulates blood pressure by converting angiotensin I to angiotensin II

Angiotensin-Converting Enzyme (ACE) is a protein that plays a crucial role in regulating blood pressure by converting angiotensin I, an inactive hormone, into angiotensin II, a potent vasoconstrictor that narrows blood vessels and increases blood pressure. ACE inhibitors are commonly used medications to treat high blood pressure and heart failure by blocking this enzyme's activity, thereby relaxing blood vessels and lowering blood pressure.

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Increased frequency of the DI genotype of the angiotensin-I converting enzyme and association of the II genotype with insulin resistance in polycystic ovary syndrome

research Increased frequency of the DI genotype of the angiotensin-I converting enzyme and association of the II genotype with insulin resistance in polycystic ovary syndrome

16 citations , April 2012 in “European Journal of Endocrinology”

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

research Association between angiotensin‐converting enzyme gene insertion deletion polymorphism and androgenetic alopecia susceptibility among Egyptian patients: A preliminary case‐controlled study

1 citations , September 2021 in “Journal of Cosmetic Dermatology”

research Studying the correlation of renin-angiotensin-system (RAS) components and insulin resistance in polycystic ovary syndrome (PCOs)

12 citations , March 2013 in “Gynecological Endocrinology”

The study found a significant link between the renin-angiotensin system and insulin resistance in women with polycystic ovary syndrome.

research Repurposing existing drugs for COVID-19: an endocrinology perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Is COVID-19 a risk factor for progression of benign prostatic hyperplasia and exacerbation of its related symptoms?: a systematic review

research Is COVID-19 a risk factor for progression of benign prostatic hyperplasia and exacerbation of its related symptoms?: a systematic review

21 citations , May 2021 in “Prostate Cancer and Prostatic Diseases”

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

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