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GlossaryAngiotensin-Converting Enzyme 2

regulates blood pressure and is a SARS-CoV-2 entry point

Angiotensin-Converting Enzyme 2 (ACE2) is a protein found on the surface of many cell types, including those in the lungs, heart, and kidneys. It plays a crucial role in regulating blood pressure by converting angiotensin II, a molecule that can increase blood pressure, into angiotensin 1-7, which has the opposite effect. ACE2 is also known for being the entry point for the SARS-CoV-2 virus, which causes COVID-19, making it a significant focus of medical research.

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research Basic mechanisms of SARS-CoV-2 infection. What endocrine systems could be implicated?

14 citations , July 2021 in “Reviews in endocrine and metabolic disorders”

SARS-CoV-2, the virus causing COVID-19, can affect all endocrine organs and systems, altering their function and potentially leading to disorders. Factors like diabetes and obesity increase infection risk and severity. Understanding these effects is key for effective treatment.

research Repurposing existing drugs for COVID-19: an endocrinology perspective

34 citations , September 2020 in “BMC Endocrine Disorders”

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Is COVID-19 a risk factor for progression of benign prostatic hyperplasia and exacerbation of its related symptoms?: a systematic review

research Is COVID-19 a risk factor for progression of benign prostatic hyperplasia and exacerbation of its related symptoms?: a systematic review

21 citations , May 2021 in “Prostate Cancer and Prostatic Diseases”

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

research Postural orthostatic tachycardia syndrome: a dermatologic perspective and successful treatment with losartan.

2 citations , August 2014 in “PubMed”

Losartan may help treat Postural Orthostatic Tachycardia Syndrome (POTS) symptoms.

research Commonalities Between COVID-19 and Radiation Injury

18 citations , October 2020 in “Radiation Research”

Some drugs may help treat both COVID-19 and radiation injury.

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