TLDR COVID-19 severely affects older adults with chronic heart, lung, or metabolic diseases.
The review from 2020 analyzed the impact of COVID-19 on patients with pre-existing chronic conditions, such as cardiac, respiratory, and metabolic diseases, highlighting their increased risk for severe outcomes. It found that conditions like hypertension, diabetes, and obesity were significant risk factors, with older patients facing higher mortality rates. The use of ACE inhibitors and angiotensin receptor blockers was debated, but not recommended for discontinuation. The pandemic disrupted routine medical care, emphasizing the need for telemedicine. The review also noted the mental health toll and suggested a potential link between male pattern baldness and severe COVID-19. It called for further research to protect vulnerable patients and manage chronic conditions during future COVID-19 waves.
119 citations
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May 2020 in “Journal of The American Academy of Dermatology” Most COVID-19 patients in hospitals have androgenetic alopecia, more in men, suggesting a link between androgen sensitivity and severe COVID-19 symptoms.
71 citations
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April 2020 in “Journal of Cosmetic Dermatology” Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.
134 citations
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April 2020 in “Journal of Cosmetic Dermatology” Male pattern hair loss could hint at androgens affecting COVID-19 severity.
34 citations
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September 2020 in “BMC Endocrine Disorders” Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
15 citations
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August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
112 citations
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July 2020 in “BMC Medicine” Women with PCOS may be at higher risk for severe COVID-19.
52 citations
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August 2021 in “Microorganisms” Higher ACE2 levels in certain tissues may worsen COVID-19 in people with other health issues, especially older adults.
68 citations
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May 2021 in “Endocrine” People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.