Racial Variations in COVID-19 Deaths May Be Due to Androgen Receptor Genetic Variants Associated with Prostate Cancer and Androgenetic Alopecia. Are Anti-Androgens a Potential Treatment for COVID-19?
April 2020
in “
Journal of Cosmetic Dermatology
”
TLDR Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.
The article suggests that genetic variations in the androgen receptor may be a contributing factor to the racial disparities in COVID-19 deaths. The authors propose that androgens may be implicated in COVID-19 disease severity and that special attention may need to be given to African Americans infected with the virus. The article suggests that anti-androgens or androgen modulating drugs may be beneficial in treating COVID-19, particularly if androgen sensitivity can be confirmed as a predisposition to SARS-Cov-2 disease severity.