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    Glossary Renin Inhibitors

    reduce blood pressure by blocking kidney enzyme activity

    Renin inhibitors, also known as renin blockers or renin antagonists, are a class of medications that reduce blood pressure by blocking the activity of renin, an enzyme produced by the kidneys. Renin plays a crucial role in the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and fluid balance. By inhibiting renin, these drugs help to lower blood pressure and are used in the treatment of hypertension.

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      research Commonalities Between COVID-19 and Radiation Injury

      18 citations , October 2020 in “Radiation Research”
      This review discusses the similarities between COVID-19 and acute radiation syndrome, highlighting their shared inflammatory responses and suggesting that insights from radiation biology could inform COVID-19 research and treatment approaches; it reports no new clinical results.

      research Repurposing existing drugs for COVID-19: an endocrinology perspective

      34 citations , September 2020 in “BMC Endocrine Disorders”
      This review highlights that while dexamethasone may reduce mortality in severe COVID-19, no other drugs have proven effectiveness for treatment, emphasizing the need for clinical trials of existing medications.

      research Beard Alopecia: An Updated and Comprehensive Review of Etiologies, Presentation and Treatment

      1 citations , July 2023 in “Journal of Clinical Medicine”
      This review provides a detailed overview of the causes, prevalence, pathophysiology, clinical presentation, and treatment of beard alopecia, highlighting conditions such as alopecia areata, pseudofolliculitis barbae, and tinea barbae, and aims to serve as a resource for clinicians handling such cases.

      research A case of treatment-resistant erosive pustular dermatosis of the scalp

      January 2025 in “SAGE Open Medical Case Reports”
      This case report described a patient with erosive pustular dermatosis of the scalp who was resistant to multiple treatments, suggesting that combination therapy may be more effective than monotherapy for managing refractory cases of this condition.

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      community Anyone tried combining Finasteride and Ashwagandha?

       4 upvotes 5 years ago
      The conversation discusses using finasteride and ashwagandha for hair loss, with some users noting potential benefits and drawbacks. Minoxidil, peppermint oil, and creatine are also mentioned, with mixed opinions on their effectiveness.

      community I had claude create a protocol only using fda approved drugs.

       4 upvotes 8 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Finasteride and “anti-aging” effects

      in Treatment  218 upvotes 1 year ago
      Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

      community DHEA, the culprit behind DUPA ? Read this!

       20 upvotes 3 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.