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GlossaryRenin Inhibitors

reduce blood pressure by blocking kidney enzyme activity

Renin inhibitors, also known as renin blockers or renin antagonists, are a class of medications that reduce blood pressure by blocking the activity of renin, an enzyme produced by the kidneys. Renin plays a crucial role in the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure and fluid balance. By inhibiting renin, these drugs help to lower blood pressure and are used in the treatment of hypertension.

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community What's "wrong" with oral minoxidil, exactly?

Unhappy_Arm_5634 in Minoxidil 173 upvotes 3 months ago

Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.

community If RU58841 is such an effective anti androgen

ConsistentLab193 in Research/Science 46 upvotes 1 year ago

RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

community 1 year 6 months fin + min + nizoral progress as diffuser who did everything right, what next?

God_i_hate_today in Progress Pictures 14 upvotes 1 year ago

The user is sharing their progress with hair loss using finasteride, minoxidil, and nizoral. They are seeking advice on what to do next for their hair. Some suggestions include switching to dutasteride, adding microneedling, or seeking another opinion from a dermatologist.

community Nearly 3 years in and I'm on a mega growth spurt. Don't lose heart.

sh1tn1nja in Chat 63 upvotes 8 months ago

The user experienced subtle hair growth improvements using finasteride, dutasteride, and minoxidil over nearly three years, with notable progress at the temples. The front hairline shows quicker regrowth cycles, but the vertex and crown remain unchanged.

community Two months of dutasteride once a day 0.5 and minoxidil 5% twice a day. The light is different but I think there is progress

ljupco82 in Is this regrowth? 96 upvotes 2 years ago

A user's experience with taking dutasteride and minoxidil for hair loss, with other users providing advice to continue treatment for at least 12 months and including dermarolling as well as dietary changes.

community Why isn’t oral minoxidil enough for me?

highlysus53 in Minoxidil 7 upvotes 11 months ago

A user takes 5mg oral minoxidil, oral dutasteride, topical tretinoin, stemoxydine, topical minoxidil, and uses dermarolling for hair loss but sees less impressive, patchy regrowth compared to others. Another person suggests some online results may be enhanced with hair fibers, not just medication.

community I feel like people here shrug off nutritional issues too quickly. Particularly for Retrograde Alopecia.

Cross_Bowman in Chat 10 upvotes 2 years ago

The user believes Retrograde Alopecia may be linked to vitamin imbalances, specifically from taking too much Vitamin E, A, Zinc, and Selenium, and suggests it could be a middle ground between Androgenic Alopecia and Telogen Effluvium. Treatments for hair loss mentioned include Androgen inhibitors and improving lifestyle factors like nutrition and sleep, with topical melatonin also recommended for Retrograde Alopecia.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

nuKaross in Research/Science 63 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community I received Kindor's KU yesterday. Is this the right way to use it?

gandalfpr in Treatment 11 upvotes 5 months ago

The user applied Kindor's KU, followed by a solution of Finasteride, Minoxidil, and Tretinoin for alopecia. They experienced no side effects from Kindor's KU.

community We all regret not acting on hair loss sooner. What is something else we can prevent if we act now?

Complex_Secretary_14 in Chat 94 upvotes 1 year ago

The conversation discusses the importance of early action in various aspects of life such as healthy eating, skincare, fitness, sleep, financial planning, and career development to prevent future health issues, regret, and financial hardship. Specific treatments mentioned include using sunscreen and tretinoin for anti-aging skincare.

community ~5 months topical minoxidil + oral finasteride results (swipe images). Slacked with minoxidil this past month, trying to wean off anyways. My last update because I’m hopping off fin and switching to RU in a few weeks (nothing to do with fin efficacy, just experimenting).

phwaaark in Progress Pictures 145 upvotes 4 years ago

The user experienced significant hair thickening after using topical minoxidil and oral finasteride for about 5 months and is considering switching from finasteride to RU58841. Other users encourage the original poster to continue the current treatment due to the positive results.

community Please explain this Minoxidil phenomena

Marius_jar in Minoxidil 57 upvotes 1 year ago

The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.

community Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant

noeyys in Research/Science 80 upvotes 6 months ago

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

community Dut (2years) / RU58841 (5 months) / Oral Min (1 year)

nuKaross in Progress Pictures 234 upvotes 2 years ago

User discusses hair loss treatment progress using Dutasteride for 2 years, RU58841 for 5 months, and oral Minoxidil for 1 year. Some users share side effects and experiences with these treatments.

community Full Album of My Results - Dermaroller/pen + minox

74775446 in Progress Pictures 587 upvotes 3 years ago

User 74775446 shares successful hair regrowth results using dermaroller/pen and minoxidil. Others discuss their experiences and concerns about finasteride side effects.

community Started fin and min on 05/02/2024

ThickMem9 in Progress Pictures 749 upvotes 6 months ago

A user shared progress pictures showing significant hair regrowth after using 1mg finasteride daily and Kirkland 5% minoxidil twice a day since 05/02/2024, along with occasional microneedling. The user reported initial headaches but no longer experiences them.

community Fin/min was honestly a miracle for me

Cappuccino541 in Progress Pictures 436 upvotes 6 months ago

A user shared progress pictures showing significant hair regrowth after using finasteride and minoxidil for six months. Other users discussed their varied experiences with these treatments and offered additional advice.

community Is this the best current Stack that doesnt involve FIN/DUT?

Necessary-Treacle-46 in Treatment 7 upvotes 5 months ago

The post and conversation are about a hair loss treatment stack without finasteride or dutasteride. The suggested treatments include Alfatradiol, Koshine826, Ketoconazole lotion, Minoxidil, microneedling, Tretinoin, and Stemoxydine.

community Will minoxidil not work if there’s too much DHT present in the scalp?

throwaway610004 in Minoxidil 5 upvotes 11 months ago

The user has been using topical finasteride and minoxidil for five months with little progress and is considering oral dutasteride to lower DHT levels, questioning if minoxidil is more effective with reduced DHT. They also use microneedling and tretinoin in their treatment routine.

community Anybody interested in a new seller option for hair loss topicals?

throwawayblahacc in Chat 6 upvotes 2 years ago

A user with hair loss is considering starting a business selling hair loss treatments, including RU58841, low-dose topical finasteride with optional minoxidil and tretinoin, and topical melatonin. They are also contemplating offering Pyrilutamide and other unique topicals, seeking feedback on interest and suggestions for their potential store.

community How does some people revive their scalps with minoxidil only?

aiamab in Minoxidil 26 upvotes 5 months ago

Some people respond better to minoxidil due to higher enzyme levels converting it to its active form. Minoxidil helps with hair regrowth but doesn't prevent hair loss; finasteride and other DHT inhibitors are needed for that.

community Stop Using Salicylic acid on your face if using minoxidil for beard growth

earthcloud5 in Product 20 upvotes 8 months ago

Salicylic acid can reduce the effectiveness of minoxidil for beard growth. Users discuss avoiding salicylic acid when using minoxidil.

community 16 months or so. Back from the dead. Age 41

Coffeepictures82 in Progress Pictures 555 upvotes 7 months ago

A user shared their 16-month hair regrowth progress using oral and topical minoxidil, dutasteride, derma rolling, and occasional keto shampoo. The conversation includes positive reactions and jokes about their impressive results.

community Miniaturized hair developing into real hair?

WorryDeep4409 in Chat 10 upvotes 4 months ago

OP is trying various treatments (finasteride, minoxidil, nizoral, dermarolling, tretinoin) to regrow hair after 8 years of baldness. Users suggest persistence and possibly adding dutasteride, noting that age and consistency affect results.

community New Latanoprost-Based Formula Used by Hollywood Celebrities

Dr_Cam in Treatment 25 upvotes 2 years ago

A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

community Impressed by the progress but think it’s time to go for the transplant?

maurauth in Progress Pictures 288 upvotes 1 year ago

The user started taking 2.5mg minoxidil tablets daily and reduced their finasteride dose to 0.5mg due to side effects. They are considering a hair transplant but are unsure if they should proceed now or wait after seeing the effects of the reduced finasteride dosage.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

Combfromhell in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

community It’s getting worse. (4 months)

Coladrive in Update 203 upvotes 1 year ago

The conversation discusses hair loss treatments, with users suggesting the use of finasteride daily, considering minoxidil for aggressive hair loss, and discussing the normalcy of shedding during treatment. Some users recommend adding Nizoral shampoo and switching to dutasteride for better results.

community Started Finasteride almost three months ago and I'm upset

ProfessionalSea1583 in Update 153 upvotes 10 months ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community He used Dutasteride for 20 years. Interview

noeyys in Treatment 112 upvotes 2 months ago

Dutasteride has been used for 20 years with some hair thickness improvement but no dramatic regrowth. The user also experimented with minoxidil, tretinoin, and peptides like BPC 157 for potential benefits in hair density and quality.