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The document shows the state of pharmaceutical patents as of 1999, focusing on treatments for various diseases.

Some drugs may help treat both COVID-19 and radiation injury.

The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.

The FDA warned about safety issues with remdesivir and tofacitinib, finasteride is linked to suicidality, potent topical corticosteroids increase osteoporosis risk, henna can cause hemolysis in G6PD deficiency, chemotherapeutic agents can cause adverse reactions, drug interactions are common in cancer patients, ketamine can reduce at-risk drinking, high dose of anticholinergics increases dementia risk in Parkinson's patients, and prenatal exposure to second-generation antipsychotics increases pregnancy complications.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Men are more likely to have severe respiratory viral infections like COVID-19 due to hormonal and genetic differences, while women generally have stronger immune responses.

Some people with primary cicatricial alopecia also have inflammatory bowel disease, suggesting a possible connection.

Mice with human chymase had a higher death rate when exposed to a toxin compared to normal mice.

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

The study found a significant link between the renin-angiotensin system and insulin resistance in women with polycystic ovary syndrome.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

The birth control pill with only progestogen can cause a false alarm in a hormone test.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

The Wnt/β-catenin pathway is important for tissue development and has potential in regenerative medicine, but requires more research for therapeutic use.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.