Lisinopril-Induced Alopecia: A Case Report

In 2016, a 53-year-old male patient with heart failure developed alopecia after over a year of taking lisinopril, an ACE inhibitor. The hair loss was resolved within 4 weeks after discontinuing lisinopril and switching to losartan potassium. The Naranjo Adverse Drug Reaction Probability Scale scored the likelihood of lisinopril causing the alopecia as 6, indicating a probable adverse drug reaction. This case adds to the evidence that alopecia may be a class effect of ACE inhibitors, marking the third such case within this drug class. Clinicians should consider lisinopril as a potential cause of unexplained alopecia, although the simultaneous initiation of coenzyme Q-10 could not be ruled out as a factor in the patient's hair regrowth.