Pharmacodynamic Evaluation: Endocrinology

    January 2017
    Michael Ab Naafs
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    TLDR The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
    In 2017, the authors reviewed the pharmacodynamics of endocrine disorders, focusing on diabetes mellitus treatments, including oral antidiabetics, insulin analogues, and their effects and side effects. They discussed the mechanisms of action and physiological effects of various hormones and their analogues, such as insulin, glucagon, and growth hormone, and their use in medical treatments. The document also covered treatments for conditions like hyperparathyroidism, osteoporosis, Cushing's syndrome, Addison's disease, and cardiovascular conditions, detailing the roles of medications like bisphosphonates, glucocorticoids, and beta-blockers. Additionally, it discussed the pharmacodynamics of sex steroids, antigonadotropins, and antiestrogens in managing conditions like menopause, heart disease, and ER-positive breast cancer. The conclusion highlighted the extensive influence of endocrinology in medicine, with many common medications falling within the categories reviewed.
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