research [Drug induced alopecia].
This article reviews various drugs reported to cause alopecia, including cytostatics and anticoagulants, but does not present new research results; it suggests that drug-related hair loss can be difficult to prove.
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research Current and Potential Agents for the Treatment of Alopecia Areata>
This review discusses current and potential treatments for alopecia areata, focusing on immunosuppressive and immunomodulatory approaches, but provides no new clinical results.
research Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits
This study found that boosting the synthesis of neural-derived 17β-estradiol effectively counteracted the impairment of hippocampal long-term potentiation caused by amyloid beta 1-42 in rat hippocampal slices, with the effect seemingly linked to glutamate NMDAR signaling.
research The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators and Myostatin Inhibitors
This article reviews the development of selective androgen receptor modulators and myostatin inhibitors as performance-enhancing drugs, highlighting ongoing challenges in achieving truly tissue-selective anabolic agents and reporting no new experimental findings.
research Vitamin A regulates dermal papilla cell proliferation and apoptosis under heat stress via IGF1 and Wnt10b signaling
This study found that vitamin A significantly enhanced the proliferation and inhibited apoptosis of rabbit dermal papilla cells under heat stress, likely by modulating miR-195/IGF1 and Wnt10b/β-catenin signaling pathways.
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5 / 183 resultscommunity Most Promising Future Hair Loss Treatments In 2026
Promising hair loss treatments in 2026 include GT20029, a topical androgen receptor degrader, and VDPHL01, an extended-release oral minoxidil, both offering safer alternatives with fewer side effects. Other treatments like sublingual minoxidil, OND-1, JW0061, TDM-105795, and AMP-303 are also being explored.
community What's "wrong" with oral minoxidil, exactly?
Oral minoxidil can boost hair growth but may cause side effects like heart palpitations and increased body hair. Many prefer topical minoxidil due to fewer side effects.
community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect
PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.
community A new study by Deng and colleagues set out to explore differences between balding and non balding scalps...
Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hair follicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.
community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?
The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.
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