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This study found that higher levels of DHA from omega-3 fatty acids delayed inflammation resolution and impaired wound healing quality in both transgenic mice and wild-type mice supplemented with DHA.

This study found that bioconjugating 16-methylheptadecanoic acid to damaged human hair can mimic the protective function of the original 18-methyleicosanoic acid, effectively restoring both the hair's external structural integrity and its internal moisture balance.

This study determined the crystal structure and conformation of synthesized 17x-Acetoxy-pregn-4,6-diene-3,20-dione, revealing specific molecular interactions and structural details in an orthorhombic crystal system.

This study found that Hataedock may alleviate atopic dermatitis symptoms in mice by maintaining skin homeostasis and improving skin barrier formation through the endocannabinoid system.

The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.

This study found a negative correlation between dietary monoene levels, particularly oleic acid, and the capacity for PGE₂ synthesis in rat skin, with the most severe skin issues noted in those fed Zephyr rapeseed oil.

This study found that bioconjugating 16-methylheptadecanoic acid (16-MHA) to damaged hair can mimic the protective properties of 18-methyleicosanoic acid (18-MEA), restoring the hair's structural integrity and moisture homeostasis, even after washing.

This study observed that new trienone compounds consistently showed higher 5alpha-reductase inhibitory activity compared to corresponding dienones across various biological models.

This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.

This study found that in a rat model, 14,15-EET may alleviate central poststroke pain by enhancing thalamic inhibition through neurosteroid signaling, potentially outperforming gabapentin in early-stage treatment.

This study found that abietic acid from pine resin more effectively inhibits testosterone 5α-reductase than several plant extracts, suggesting potential for treating androgen-dependent diseases.

In this study, researchers successfully synthesized a rigid 3a-arylhexahydropentalene-1,6-dione from the easily accessible starting material cyclopent-2-en-1-one, highlighting a structural motif common in natural products and pharmaceuticals.

In this study, mice fed various high-fat diets showed changes in dermal white adipose tissue lipid composition, with decreases in essential omega-3 fatty acids, which are important for skin health.

This study reported that a 19-year-old man's essential fatty acid deficiency was reversed with daily topical application of linoleic acid, improving clinical symptoms and normalizing certain fatty acid levels.

In this case report, applying linoleic acid topically reversed essential fatty acid deficiency and related skin symptoms in a patient receiving long-term fat-free intravenous nutrition.

This study found that both new and old formulas of DCP for treating alopecia areata resulted in similar hair regrowth, but tolerance was significantly better with DCP in isopropanol.

In this study, cyproterone acetate combined with estradiol dramatically improved hirsutism symptoms and significantly reduced plasma testosterone and androstenedione levels in patients over periods of up to three years.

This study reports the crystal structure of C28H32O5, revealing its monoclinic symmetry, unit-cell dimensions, and molecular conformation.

This study found that caffeic acid amide derivative, compound 4, effectively inhibited steroid 5α-reductase type 1 in vitro, suggesting potential for development as a treatment for androgenic alopecia.

This study developed a new competitive 5alpha-reductase inhibitor with an IC(50) of 0.84 microM using a novel chemical structure.

The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

This review discusses the essential role of linoleic acid in preventing deficiency symptoms and enhancing skin function, but notes that scientific knowledge on its potential therapeutic use for skin diseases remains limited.

This study found that diphlorethohydroxycarmalol significantly increased prostaglandin $E_2$ synthesis in HaCaT human keratinocytes by upregulating COX-1 and COX-2 expression, suggesting potential benefits from elevated $PGE_2$ production.

This study found that the acyl-CoA binding protein is essential for the production of very long chain free fatty acids in the stratum corneum and maintaining normal epidermal barrier function in mice.

This letter discusses how outdated measurement technology may obscure evidence of essential fatty acid deficiency in low-fat diet patients, potentially leading to undiagnosed EFA insufficiencies related to heart disease.

In this study, a treatment regimen combining cyproterone acetate and ethinyl estradiol significantly improved acne and seborrhoea in most women after three months, but had varied effects on hirsutism and alopecia.

This study reports that while DCP had similar treatment efficacy in propylene glycol and isopropanol for alopecia areata, the formulation in isopropanol was better tolerated.

This study found that the EtOAc extract of Tridax procumbens aerial parts significantly inhibited rat paw edema and COX enzyme activity, suggesting its potential anti-inflammatory properties.

This study observed that PCE-DP may improve skin pigmentation by increasing epidermal turnover and inhibiting melanin uptake and inflammation in human epidermal keratinocytes.