Docosahexaenoic Acid Slows Inflammation Resolution and Impairs the Quality of Healed Skin Tissue

November 2019 in “ Clinical Science ”

Thamiris Candreva, Carolina Meneguetti Cintra Kühl, Beatriz Bürger, MARIAH B. P. DOS ANJOS, Márcio Alberto Torsoni, Sílvio Roberto Consonni, Amanda Rabello Crisma, Helena L. Fisk, Philip C. Calder, Felipe Cézar Pinheiro de Mato, Erica Moraes Sernaglia, Marco Aurélio Ramirez Vinolo, Hosana Gomes Rodrigues

docosahexaenoic acid omega-3 fatty acids DHA FAT-1 transgenic mice wild-type mice DHA-enriched fish oil TNF-α IL-10 collagen fibers fish oil tumor necrosis factor alpha interleukin-10

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Studysummary This study found that higher levels of DHA from omega-3 fatty acids delayed inflammation resolution and impaired wound healing quality in both transgenic mice and wild-type mice supplemented with DHA.

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