Diagnosing Essential Fatty Acid Deficiency

    June 1998 in “ Circulation
    Eduardo N. Siguel
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    TLDR Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.
    The document from 1998 discussed the diagnosis of essential fatty acid (EFA) deficiency, critiquing the high triene/tetraene (T/T) ratio used by Dr. Gould and colleagues, which Dr. Siguel argued led to underdiagnosis due to outdated technology. Siguel emphasized the health risks of even mild EFA insufficiency, such as abnormal lipid levels, hypertension, and coronary artery disease, and warned that low-fat diets and fat substitutes could worsen EFA insufficiency. The document also noted that EFA deficiency is rare in free-living adults but can occur in those on very low-fat diets, leading to symptoms like memory loss and visual issues, which improve with increased EFA intake. It recommended maintaining at least 10% of calories from fat and using specific oils like soybean and walnut oil to meet EFA requirements.
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