Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This research highlights advancements in understanding and treating psoriasis, finding that targeted therapies like IL-17 and IL-23 inhibitors show promise, but challenges such as adverse events, treatment resistance, and the need for personalized approaches remain.

This literature review provides insights into the multifactorial causes of hair loss, highlighting genetic, hormonal, immune, and environmental factors, and summarizes preventive strategies like balanced nutrition and stress management to promote healthier hair.

This review, drawing on scientific literature, explores alopecia areata's pathogenesis and treatment, noting that while therapies like JAK inhibitors show promise, there remains a significant need for more effective and targeted solutions, and a better understanding of the disease mechanisms.

This review explored the complex mechanisms behind androgenetic alopecia, highlighting genetic influences and factors like increased 5-α reductase and androgen receptors in hair follicles, while identifying microinflammation and oxidative stress as related issues.

This study found that a pathogenetically-based treatment using drugs to correct dyslipidemia and insulin resistance in conjunction with basic therapy led to better outcomes for alopecia areata patients with metabolic syndrome.

This case report describes a novel NECTIN4 gene mutation linked to ED-syndactyly syndrome 1 in a young girl, contributing to the understanding of this rare ectodermal dysplasia.

This pilot study suggests that lovastatin may counteract stress-induced MICA expression in hair follicles and enhance MICA shedding, potentially offering a complementary approach for alopecia areata treatment.

This review outlines the proposed theories behind the development of alopecia areata, emphasizing the autoimmune process involving lost immune privilege in hair follicles, and stresses the need to pinpoint specific pathogenic mechanisms for potential treatments.

This article reviews neuroendocrine abnormalities in polycystic ovarian syndrome and reports no new findings, highlighting areas such as the hypothalamus-pituitary axis and genetic basis.

This study found that trichilemmal carcinoma shares genetic changes with other skin cancers, suggesting a similar pathogenesis, particularly in those with aggressive clinical courses linked to TP53 mutations.

This study reported genetic mutations in trichilemmal carcinoma similar to those found in other skin cancers, including TP53 mutations associated with aggressive disease.

This study found that mutations in the PADI3 gene, which is important for hair shaft formation, may contribute to central centrifugal cicatricial alopecia among patients.

CCCA in women of African ancestry may be caused by PADI3 gene mutations and intense hair grooming.

In this study, researchers found that alopecia areata patients show a significant reduction in suppressive regulatory T-cells and an increase in inflammatory T-cell populations, suggesting an immunological imbalance contributing to the disease.

This study observed that stress, as indicated by hair cortisol concentrations, may trigger onset of hair loss in alopecia areata, although the findings were not statistically significant.

This study suggests that differential expression of miRNAs in hair follicles from the frontal and occipital scalp may contribute to the androgen-dependent changes seen in male pattern baldness.

This article discusses telogen effluvium in women, its causes, and typical diagnostic methods, but reports no new research findings on clinical outcomes or treatments.

This chapter reviews the causes, clinical characteristics, and modern management of male and female pattern hair loss but reports no new clinical results.

Androgenetic alopecia may be irreversible due to the detachment of a muscle from hair follicles.

This review discusses treatments for androgenic alopecia, noting that current options like finasteride and minoxidil are effective for only 10% of patients, thus highlighting the need for new therapies.

This study observed that hormone replacement therapy and autoimmune diseases may be more common among women with frontal fibrosing alopecia compared to those with androgenetic alopecia.

Androgenetic alopecia, a common hair loss condition, can affect mental health and there are various medical treatments available for it.

This review discusses recent advances in understanding acne pathobiology, highlighting the potential for developing new customized therapies, but it reports no new clinical findings.

This review discusses recent insights into the role of regulatory T cells in psoriasis and the impact of current treatments on their function, but reports no new research findings.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

This review discusses the mechanisms linking obesity and polycystic ovary syndrome and explores potential management options, but it presents no original research findings.

This review noted that alopecia areata is an autoimmune disease impacting hair follicles and offered insights into its complex pathogenesis involving immune responses, while highlighting ongoing research into new treatments such as Janus kinase inhibitors and other immunomodulatory drugs.

This review explores animal models of alopecia areata, particularly focusing on the insights they've provided into the disease's immune mechanisms and potential treatment approaches, without reporting new experimental data.

This review summarizes factors involved in polycystic ovary syndrome pathogenesis and management, highlights commonly prescribed and repurposed medications, and calls for well-designed clinical trials to evaluate these treatments further.