Erosive Pustular Dermatosis of the Scalp: A Pathogenetic Mystery and Therapeutic Challenge

    July 2022 in “ Dermatology Reports ”
    Georgi Tchernev, Simona Kordeva, Ilia Batashki, Atanas Batashki, Heily Kirilova, Konstantin Stavrov
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    TLDR A rare scalp condition called Erosive pustular dermatosis is hard to diagnose and treat.
    Erosive pustular dermatosis of the scalp (EPD) is a rare condition that primarily affects adults with photo-damaged bald scalps. The condition presents with large erythematous, erosive, and crusted patches with granulation on atrophic skin. Diagnosis can be challenging due to non-specific clinical and histopathological findings, making biopsy and careful histopathological verification essential. The histopathology findings typically include superficial erosions with mild neutrophil infiltrate, focal parakeratosis, smoothed rete ridges without pronounced interface changes, and a pronounced lymphoplasmacytic infiltrate with focal distribution in the dermis. The study reports a case of a 58-year-old male patient with a 1-year-old lesion initially suspected to be skin cancer, but later diagnosed with EPD. The patient was successfully treated with topical clobetasol proprionate after 3-5 weeks.
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