TLDR Alopecia areata causes varying hair loss and nail changes, and treatments include topical, systemic, and injectable therapies.
The document discussed the clinical presentation, pathogenesis, and treatment options for alopecia areata (AA), highlighting the variability in its clinical manifestations, from small patches of hair loss to complete hair loss on the body and scalp. It emphasized the importance of trichoscopy and scalp biopsy in diagnosing AA and noted that nail changes, present in up to 66% of patients, could indicate more severe disease progression. The review also covered various treatment approaches, including topical, systemic, and injectable therapies, with a focus on the potential of Janus kinase inhibitors. The importance of a thorough nail examination in AA patients was stressed, as nail changes, though often subtle and asymptomatic, could significantly impact quality of life and suggest disease progression.
45 citations,
January 2018 in “International Journal of Dermatology” Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.
290 citations,
December 2017 in “Journal of The American Academy of Dermatology” Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.
182 citations,
December 2017 in “Journal of the American Academy of Dermatology” Some treatments can help with a hair loss condition called alopecia areata, but none ensure lasting results; choices depend on the person, with JAK inhibitors showing promise for severe cases.
148 citations,
December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations,
November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
110 citations,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
