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High doses of certain vitamins can cause serious side effects and health risks.

Chemotherapy provides symptom relief and extends life in 30-50% of gynecological cancer cases, but has only cured choriocarcinoma.

Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.

Higher early lead exposure is linked to delayed puberty in girls.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.

A woman with a rare hormone resistance condition also had missing teeth and hair loss, which might be new symptoms of her genetic disorder.

Clomiphene citrate is a cheap and simple treatment for low testosterone that works as well as human chorionic gonadotropin, alone or combined, especially for men who want to keep their fertility.

Treating early puberty with hormone therapy may increase the risk of polycystic ovary syndrome in adults.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

Hyperthyroidism can hide signs of high androgen levels in females.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

Childhood obesity is rising globally due to various factors, and early prevention and healthy lifestyle changes are crucial.

Oestrogens are key for bone growth during puberty in both boys and girls.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Certain drugs that block specific enzymes can help treat prostate diseases.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.

Sardinians were historically short due to a mix of genetics and factors like disease and poor nutrition, but recent height increases suggest better living conditions had a bigger impact.

Finasteride negatively affects fish reproduction and gonadal development.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.