Response to Falotico et al's 'Perils of Biotin Supplementation'

    Jacob Nosewicz, Natalie Spaccarelli, Kristen Roberts, Phil A. Hart, Jessica Kaffenberger, John Trinidad, Benjamin H. Kaffenberger
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    Studysummary This review discusses the risk factors, clinical presentation, diagnosis, and management of dermatoses linked to B-complex vitamin deficiencies, including biotin, but does not address risks from over-supplementation. Our plain-language summary of this paper — not a Tressless recommendation.
    In response to Falotico et al.'s concerns about biotin supplementation, the authors of the original article on B-complex vitamin deficiencies clarify that their review focused on the risk factors, clinical presentations, diagnostic methods, and treatments for dermatoses caused by these deficiencies. They acknowledge that due to publication length constraints, they did not address the potential risks of over-supplementation or toxicity of micronutrients. The original article highlighted the clinical signs of biotin deficiency, such as skin eruptions and alopecia, and discussed the effective management of these conditions with biotin supplementation.
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