TLDR Some vitamins, amino acids, and alternative medicines can cause serious side effects, including bone, muscle, and skin issues, and healthcare professionals should be aware of these risks.
The document reviews various adverse effects associated with vitamins, amino acids, nutrition, and complementary and alternative medicine. It highlights musculoskeletal, mucocutaneous, electrolyte abnormalities, and bone adverse effects of vitamin A derivatives, including bone marrow necrosis and idiopathic intracranial hypertension from all-trans retinoic acid, and hair loss from isotretinoin. Niacin overdose was misdiagnosed as anaphylaxis, emphasizing the need for careful identification. Additionally, complementary and alternative medicine products caused unique adverse effects across multiple systems, such as drug-induced liver injury from curcumin and green tea, and allergic contact dermatitis from cinnamon.
7 citations,
May 2022 in “International Journal of Environmental Research and Public Health” Isotretinoin therapy for acne can cause many reversible side effects, mainly mild skin conditions, and patient understanding of these effects can improve treatment adherence.
6 citations,
February 2022 in “JAAD International” Higher doses of isotretinoin may lead to more hair loss.
1 citations,
November 2021 in “British Journal of Clinical Pharmacology” Saw palmetto may cause erectile dysfunction and needs better safety monitoring.
31 citations,
January 1981 in “Pharmacology & Therapeutics” Oral retinoids are effective for treating severe skin disorders but have reversible side effects and risks for pregnant women.
January 1982 in “Side effects of drugs annual” High doses of certain vitamins can cause serious side effects and health risks.
Some medications, including retinoids, antifungals, and psychotropic drugs, can cause reversible hair loss if stopped or doses are reduced.
60 citations,
January 2014 in “Anais Brasileiros De Dermatologia” Nanotechnology in dermatology shows promise for better drug delivery and treatment effectiveness but requires more safety research.
1 citations,
August 2013 in “Springer eBooks” Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.
