Evaluation of Serum G Protein-Coupled Estrogen Receptor 1 (GPER-1) Levels in Patients with Androgenetic Alopecia

July 2021 in “ Archives of Dermatological Research ”

Perihan Öztürk, Ergul Belge Kurutas, Mahmut Kus

androgenetic alopecia G protein-coupled estrogen receptor 1 GPER-1 AGA

TLDR Alopecia patients have less GPER-1, which might affect hair loss.

The study found that people with androgenetic alopecia have lower levels of serum GPER-1 compared to healthy individuals, suggesting that GPER-1 may play a role in the development of the condition. The study included 40 AGA patients and 40 healthy controls. Further research is needed to confirm these findings and explore potential therapeutic implications.

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Evaluation of the Relationship Between Serum G Protein-Coupled Estrogen Receptors (GPER-1) Levels and the Severity and Duration of the Disease in Patients with Androgenetic Alopecia: A Case-Control Study

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Evaluation of Serum G Protein-Coupled Estrogen Receptor 1 (GPER-1) Levels in Patients with Androgenetic Alopecia

Research cited in this study

research Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens

research Human Scalp Hair: Modulation by Various Factors and Hormones - Do Estrogens Inhibit or Stimulate? A Perplexing Perspective

research Apoptosis in Follicles of Individuals with Female Pattern Hair Loss Is Associated with Perifollicular Microinflammation

research Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update

research Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey

research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss

research The Hair Follicle as an Estrogen Target and Source

research An Estrogen Receptor Pathway Regulates the Telogen-Anagen Hair Follicle Transition and Influences Epidermal Cell Proliferation

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