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Deleting the p63 gene in certain cells causes problems in thymus development and severe hair loss in mice.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Low selenium levels can extend lifespan but worsen health issues.

UV exposure causes hair thinning, graying, and changes in hair growth cycles in mice.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

Targeting ornithine decarboxylase can help prevent skin cancer.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Inhibiting ornithine decarboxylase may help prevent certain skin cancers.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

Prolactin may affect hair growth differently based on gender and scalp area.

ΔNp63α helps control a protein that stops cancer cells from spreading.

The treatment was ineffective in humans.

The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Sulforaphane may help with hair growth by breaking down a hormone that causes hair loss.

Runx genes are important for stem cell regulation and their roles in aging and disease need more research.

Integrin alphavbeta6 is important for wound healing and hair growth, and blocking it may improve these processes.

Noggin is necessary to start the hair growth phase in skin after birth.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Meis1 is crucial for skin health and tumor development.

Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Mice without the vitamin D receptor are more prone to UV-induced skin tumors.

C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.