Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion in Mice Through Enhancer Dynamics

    July 2023 in “ Communications biology ”
    Roman Thaler, Keigo Yoshizaki, Thai Nguyen … Yuko Oda
    Studysummary In this study, researchers found that deleting Med1, a key epigenetic regulator in dental epithelia, led to hair growth on mouse incisors by altering enhancer landscapes and causing a switch from dental to hair lineage transcription programs.
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    Research cited in this study 12

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