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    Glossary Oxidative Stress

    imbalance between free radicals and antioxidants causing cellular damage

    Oxidative stress refers to an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants (molecules that neutralize free radicals) in the body. This imbalance can lead to cellular damage, also known as oxidative damage or oxidative injury, and is implicated in various conditions, including aging, cancer, and hair loss disorders like alopecia.

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    1. Targeting Oxidative Stress and Mitochondrial Dysfunction in the Treatment of Impaired Wound Healing: A Systematic Review Antioxidants · 2018 · 280 citations
    2. Senile hair graying: H <sub>2</sub> O <sub>2</sub> ‐mediated oxidative stress affects human hair color by blunting methionine sulfoxide repair The FASEB Journal · 2009 · 217 citations
    3. Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis Archives of Toxicology · 2018 · 215 citations
    4. Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage ˜The œFASEB journal · 2006 · 210 citations
    5. Oxidative stress in ageing of hair International Journal of Trichology · 2009 · 126 citations
    6. Oxidative Stress–Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia Journal of Investigative Dermatology · 2015 · 93 citations
    7. Oxidative stress and autoimmune skin disease 2013 · 73 citations
    8. Age-induced hair greying - the multiple effects of oxidative stress International Journal of Cosmetic Science · 2013 · 67 citations
    9. Role of Oxidative Stress in Polycystic Ovary Syndrome Current Women's Health Reviews · 2010 · 65 citations
    10. Oxidative Stress in Alopecia Areata: A Case–Control Study American Journal of Clinical Dermatology · 2013 · 62 citations
    11. The impact of oxidative stress on hair International Journal of Cosmetic Science · 2015 · 59 citations
    12. Oxidative Damage Control in a Human (Mini-) Organ: Nrf2 Activation Protects against Oxidative Stress-Induced Hair Growth Inhibition Journal of Investigative Dermatology · 2016 · 58 citations
    13. Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress International Journal of Nanomedicine · 2016 · 43 citations
    14. Oxidative stress in hair follicle development and hair growth: Signalling pathways, intervening mechanisms and potential of natural antioxidants Journal of Cellular and Molecular Medicine · 2024 · 41 citations
    15. Scalp condition impacts hair growth and retention via oxidative stress International journal of trichology · 2018 · 40 citations
    16. Oxidative Stress and Skin Diseases: The Role of Lipid Peroxidation Antioxidants · 2025 · 36 citations
    17. Polycystic ovary syndrome and its management: In view of oxidative stress BioMolecular Concepts · 2024 · 35 citations
    18. Investigation of oxidative stress in patients with alopecia areata and its relationship with disease severity, duration, recurrence and pattern Clinical and experimental dermatology · 2014 · 35 citations
    19. Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond? BioEssays · 2017 · 30 citations
    20. Platelets Facilitate Wound Healing by Mitochondrial Transfer and Reducing Oxidative Stress in Endothelial Cells Oxidative Medicine and Cellular Longevity · 2023 · 27 citations
    21. Exploring the Antioxidative Effects of Ginger and Cinnamon: A Comprehensive Review of Evidence and Molecular Mechanisms Involved in Polycystic Ovary Syndrome (PCOS) and Other Oxidative Stress-Related Disorders Antioxidants · 2024 · 24 citations
    22. Quaternary ammonium iminofullerenes improve root growth of oxidative-stress maize through ASA-GSH cycle modulating redox homeostasis of roots and ROS-mediated root-hair elongation Journal of Nanobiotechnology · 2022 · 24 citations
    23. C‐reactive protein promotes adhesion of monocytes to endothelial cells via NADPH oxidase‐mediated oxidative stress Journal of Cellular Biochemistry · 2012 · 24 citations
    24. Foxp1 Regulates the Proliferation of Hair Follicle Stem Cells in Response to Oxidative Stress during Hair Cycling PloS one · 2015 · 22 citations
    25. The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-communicable Chronic Disease Antioxidants · 2021 · 16 citations
    26. Evaluation of Serum Paraoxonase, Arylesterase, Prolidase Activities and Oxidative Stress in Patients with Alopecia Areata Skin pharmacology and physiology · 2018 · 16 citations
    27. Alopecia Areata: A Review of the Role of Oxidative Stress, Possible Biomarkers, and Potential Novel Therapeutic Approaches Antioxidants · 2023 · 15 citations
    28. Effect of Fermented Camel Milk Containing Pumpkin Seed Milk on the Oxidative Stress Induced by Carbon Tetrachloride in Experimental Rats Fermentation · 2022 · 15 citations
    29. Free androgen index (FAI)’s relations with oxidative stress and insulin resistance in polycystic ovary syndrome Scientific Reports · 2023 · 14 citations
    30. Argan (Argania Spinosa) press cake extract enhances cell proliferation and prevents oxidative stress and inflammation of human dermal papilla cells Journal of dermatological science · 2021 · 14 citations