TLDR Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.
The study investigated the effects of finasteride on brain oxidative stress and acetylcholinesterase activity in acute thioacetamide-induced hepatic encephalopathy in rats. The results showed that finasteride had regionally different effects on brain oxidative stress and acetylcholinesterase activity, with some regions showing increased oxidative stress and decreased acetylcholinesterase activity, while others showed the opposite. The study suggests that finasteride may have potential therapeutic effects in hepatic encephalopathy, but further research is needed to fully understand its mechanisms of action.
17 citations,
November 2014 in “American Journal of Physiology-gastrointestinal and Liver Physiology” Finasteride helps brain function in rats with liver-related brain issues.
15 citations,
October 2014 in “Hormone Molecular Biology and Clinical Investigation” Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
61 citations,
September 2008 in “Biological & Pharmaceutical Bulletin” Finasteride almost fully depletes allopregnanolone in rat brains and enhances 20α-DHP, but doesn't change 3α-DHP levels.
11 citations,
July 2008 in “European Journal of Drug Metabolism and Pharmacokinetics” Finasteride helps reduce pain and inflammation in animals.
54 citations,
August 2005 in “Alcohol” Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
14 citations,
March 2018 in “Translational Stroke Research” Finasteride helps protect brain in old male rats.
January 2020 in “Brazilian Journal of Pharmaceutical Sciences” Finasteride worsens heart damage from nandrolone decanoate but protects against cell damage.
November 2020 in “Psychoneuroendocrinology” Finasteride might affect memory by impacting cholinergic system.
6 citations,
October 2017 Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
7 citations,
December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
