Finasteride Improves Motor, EEG, and Cellular Changes in Rat Brain in Thioacetamide-Induced Hepatic Encephalopathy

August 2014 in “ American Journal of Physiology-gastrointestinal and Liver Physiology ”

Dušan Mladenović, Dragan Hrnčić, Nataša Petronijević, Goran Jevtić, Tatjana Radosavljević, Aleksandra Rašić-Marković, Nela Puškaš, Nebojša Maksić, Olivera Stanojlović

finasteride Propecia

Studysummary This study found that finasteride significantly improved motor, EEG, and cellular changes in a rat model of thioacetamide-induced hepatic encephalopathy and prevented the development of hepatic coma.

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The study investigated the effects of finasteride on motor, EEG, and cellular changes in rat brains with thioacetamide-induced hepatic encephalopathy. The results showed that finasteride improved motor function, reduced EEG abnormalities, and decreased lipid peroxidation in the brain. The study suggests that finasteride may have a therapeutic effect on hepatic encephalopathy.

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