The Potential Involvement of Cholinergic System in Finasteride Induced Cognitive Dysfunction

November 2020 in “ Psychoneuroendocrinology ”

Ashutosh Ahire, Kala P. Nair, B.S. Shankaranarayana Rao, B.N. Srikumar

finasteride cholinergic system cognitive dysfunction Propecia

Studysummary In this study, repeated finasteride administration was associated with decreased social interaction and cognitive deficits in male rats, potentially linked to changes in cholinergic system activity. Our plain-language summary of this paper — not a Tressless recommendation.

Finasteride, a drug used for hair loss, may cause cognitive dysfunction by affecting the cholinergic system, according to multiple studies on rats. However, further research is needed to confirm this potential side effect and understand the underlying mechanisms. The cholinergic system may play a role in the cognitive effects of finasteride, but more research is necessary to fully understand this connection.

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