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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.

Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Scientists created 3D hair-like structures that could help study hair growth and test treatments.

A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.

Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.

Sensitive skin often causes discomfort, affects many people, especially women and older adults, and should be managed with careful product selection.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Safflower has been used in traditional medicine for centuries and shows promise in treating heart, brain, and inflammatory conditions, but more research is needed to ensure its safety.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Monoolein-alginate beads help heal wounds by controlling moisture and effectively delivering adenosine to the skin.

Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.

Using special RNA to target a mutant gene fixed hair problems in mice.

Estrogen is important for keeping adult mouse nipple skin healthy by controlling certain cell signals.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Centella asiatica extract may help promote hair growth.

Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.

The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.

Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.

Two microRNAs affect hair follicle development in sheep by targeting specific genes.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.

A special stem cell fluid can speed up wound healing and hair growth in mice.

Human skin cells with stem-like features can help create new hair follicles and sebaceous glands when combined with other cells.

Different fibroblasts play key roles in skin healing and scarring.

Human dermal stem cells can become functional skin pigment cells.

Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.