2 citations
,
October 2001 in “Analytical Sciences” A new compound that could treat various androgen-related conditions was created and analyzed.
4 citations
,
March 2023 in “Molecules/Molecules online/Molecules annual” This study successfully extracted gallic acid and ferulic acid using a biocompatible aqueous two-phase system, suggesting a sustainable approach for producing antioxidants as food supplements for hair health.
January 2024 in “La Ciencia al Servicio de la Salud y Nutrición” This narrative review attributes antiandrogenic properties to spironolactone, reporting its effectiveness in treating dermatological conditions like alopecia androgenica, acne, and hirsutism, though highlighting necessary attention to potential adverse effects and contraindications.
June 2024 in “Molecules/Molecules online/Molecules annual” This study found that Platycladus orientalis flavonoids may reduce oxidative damage and slow melanin degradation in AGA-affected hair, improving its quality.
1 citations
,
November 2023 in “Indian Journal of Science and Technology” In this study, researchers identified several active metabolites in Eclipta alba, demonstrated strong interaction with Alzheimer's disease proteins, and found that 28 days of treatment improved memory without significant toxicity in rats, suggesting potential pathways for treating Alzheimer's.
9 citations
,
May 2021 in “Molecules” This review discusses indole-based bifunctional aldose reductase inhibitors and antioxidants for diabetic complications and chronic inflammation-related pathologies, but reports no new clinical results.
8 citations
,
July 2018 in “Analytical sciences” This study reported that derivatization with 5-butylpicolinic acid improved the sensitivity for detecting testosterone and DHT in saliva using LC-ESI-MS/MS, with minimal interference from the saliva matrix.
January 2021 in “Journal of cosmetology & trichology” This study suggests that L-(+)-Tartaric Acid may support hair growth by up-regulating certain genes in human Dermal Papilla cells, making it a potentially useful additive in minoxidil formulations.
24 citations
,
January 2014 in “The American Journal of Chinese Medicine” This review compiles data on Platycladus orientalis leaves, noting their diverse pharmacological activities and advocating for more research to clarify their traditional blood-cooling and hematostatic uses.
February 2024 in “Scientific Reports” In this study, cinnamic acid was found to enhance hair growth in human dermal papilla cells and hair follicle organoids by activating oxytocin signaling, suggesting its potential for developing hair growth-promoting products.
April 2017 in “Journal of Investigative Dermatology” This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.
January 2024 in “Biochemistry Research International” This study found that compounds from Ziziphus spina-christi roots exhibited promising antibacterial and antioxidant activities, supporting its traditional medicinal use.
7 citations
,
October 2018 in “South African journal of botany” This study found that the plant Clausena anisata exhibited promising antimicrobial, antioxidant, and anti-inflammatory activities against acne-causing bacteria and inflammation, suggesting its potential as a candidate for further anti-acne treatment research.
29 citations
,
January 2020 in “BioMed Research International” This study found that sinapic acid promotes the browning of 3T3-L1 adipocytes and may offer therapeutic potential for obesity by influencing mitochondrial biogenesis through the p38 MAPK/CREB signaling pathway.
August 2025 in “Current Botany” This study suggests that Acrotrema arnottianum, a herb used in traditional medicine, contains biologically active metabolites like squalene and α-Tocopherol. It showed antibacterial effects against Staphylococcus aureus and antifungal properties against Candida albicans, while demonstrating antioxidant activity.
This review explores the potential of carnosic acid, a compound found in rosemary and sage, as a natural alternative treatment for alopecia, highlighting its antioxidant, anti-inflammatory, and hair follicle-regenerative properties, though its poor solubility and stability remain challenges for clinical application.
3 citations
,
November 2022 in “Molecules/Molecules online/Molecules annual” This study found that ingesting Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. extract promoted hair regrowth and follicle maturation in mice by enhancing cytoprotective effects and growth factor expression.
5 citations
,
September 2019 in “The Open biomarkers journal” This study found that linoleic acid may help protect against acrylamide toxicity in female albino rats.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports the discovery of LX-38, a novel non-steroidal drug candidate that may offer safer treatment for conditions like Benign Prostatic Hyperplasia by avoiding hormonal side effects associated with current therapies.
July 2023 in “Journal of the Mexican chemical society” This study found that Hibiscus rosa-sinensis dried leaves extract displayed the strongest pancreatic lipase inhibitory activity among 37 tested plant extracts, showing potential as an anti-obesity agent with effects comparable to the pharmaceutical drug orlistat in reducing plasma triacylglycerol levels in rats.
10 citations
,
October 1993 in “Archives of dermatological research” The researchers reported that the antipsoriatic compounds 1,25-dihydroxy-vitamin D3 and calcipotriol thinned the living cell compartment in organotypic ORS cultures by accelerating the differentiation pathway rather than affecting proliferation.
15 citations
,
June 2018 in “Journal of Chromatographic Science” This study successfully developed a method to measure four flavonoids from Platycladus orientalis leaves in rat plasma, which was used in a pharmacokinetic study on healthy rats.
29 citations
,
October 2009 in “Pharmacology Biochemistry and Behavior”
September 2018 in “한국자원식물학회지” This study found that oregonin isolated from Alnus japonica exhibits strong antioxidant activity and may promote hair growth, suggesting its potential use in cosmetic products.
September 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study suggests that a topical hydroalcoholic extract of liquorice root significantly reduced sebaceous gland size in Syrian hamsters, indicating potential for use in anti-acne therapy.
September 2025 in “Plants” In this study, the wood essential oil of *Juniperus morrisonicola* exhibited significant anti-inflammatory activity, notably inhibiting nitric oxide production in stimulated macrophages, and showed cytotoxic effects against liver cancer cells, suggesting its potential for drug development and eco-friendly applications.
2 citations
,
April 2024 in “Science & Technology Indonesia” In this study, extracts from the bark of Albizia saponaria, particularly the ethyl acetate fraction, showed significant antioxidant activity, potentially due to its high phenolic and flavonoid content, suggesting its usefulness as a source of antioxidants for pharmaceutical formulations.
1 citations
,
February 2025 in “Frontiers in Nutrition” This study found that a postbiotic derived from hawthorn and probiotics can alleviate loperamide-induced constipation in aged mice by regulating several physiological processes, including intestinal water and sodium metabolism, maintaining gut flora and barrier, reducing inflammation, and enhancing short-chain fatty acid metabolism.
13 citations
,
January 2017 in “Chemical & Pharmaceutical Bulletin” This study found that a synthetic avicequinone C analogue, 5e, was significantly more potent in inhibiting steroid 5α-reductase type 1 activity in human keratinocytes compared to the original isolated compound.
1 citations
,
September 2025 in “Archivio Italiano di Urologia e Andrologia” In this study, the combination of Serenoa repens extract with Phenolmicin P3 and Bosexil suppositories significantly improved lower urinary tract symptoms and decreased PSA levels in patients with benign prostatic obstruction-related symptoms.