Anti-Acne Activity of Lipido-Sterolic Extract of Serenoa Repens and Hydro-Alcoholic Extract of Glycyrrhiza Glabra in Syrian Hamster Ear Model

The study investigated the anti-acne potential of lipido-sterolic extract of Serenoa repens and hydro-alcoholic extract of Glycyrrhiza glabra using a Syrian hamster ear model. Acne vulgaris, a common dermatological condition, is influenced by androgens that increase sebum production, leading to acne development. The research focused on reducing sebum production as a treatment strategy. The study found that the topical application of a 3% w/v hydro-alcoholic extract of liquorice roots significantly reduced the area of sebaceous glands in the hamster ear model. These results suggested that liquorice could be a promising natural treatment for acne due to its antiandrogenic properties.