8 citations
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August 2022 in “Pharmaceutics” This study found that erythrocyte-anchored CPA-encapsulated nanoparticles improved the delivery and accumulation of Cepharanthine in the lungs, enhancing its effectiveness in treating acute lung injury by reducing inflammatory responses.
27 citations
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September 2018 in “Medicines” This study reported that oleic acid-based nanovesicles improve follicular delivery and reduce side effects of minoxidil compared to traditional MXD lotions.
4 citations
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October 2024 in “Heliyon” This study characterized the CYP154C7 enzyme from *Streptomyces* sp. PAMC26508, highlighting its ability to hydroxylate steroids efficiently, particularly androstenedione, and identified key amino acids important for substrate selectivity and catalytic efficiency.
36 citations
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January 2019 in “Nature communications” This study found that Ldh activity in hair follicle stem cell-mediated squamous cell carcinoma is not necessary for tumorigenesis, as its modulation did not affect the cancer's development or characteristics.
232 citations
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June 1975 in “Journal of Steroid Biochemistry” In this study, a treatment regimen combining cyproterone acetate and ethinyl estradiol significantly improved acne and seborrhoea in most women after three months, but had varied effects on hirsutism and alopecia.
February 2026 in “Molecules” This study reported that a novel nanomedicine combining berberine and sinapic acid significantly inhibited the growth of mouse mammary carcinoma cells and demonstrated an anti-tumor effect in vivo, without significant systemic toxicity after 28 days, suggesting a promising, low-toxicity therapeutic strategy for breast cancer.
March 2018 in “International Pharmacy Acta” This study concluded that niosomes could effectively serve as stable carriers for topical aminexil delivery, showing promising stability and a slow, biphasic release profile in laboratory settings.
62 citations
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December 2007 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that enzymatic conversion of Arg-51 in S100A3 protein to citrulline promotes homotetramer assembly, potentially increasing Ca²⁺ binding required for hair cuticular barrier formation.
This study highlights that azelaic acid, initially recognized for skin hypopigmentation, shows potential in treating various skin conditions due to its complex mechanisms, even though these are not yet fully understood, indicating a need for further research.
January 1995 in “Revista de arqueología” In this study, the vitamin D analogues 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol were found to thin the living cell layer and affect differentiation marker expression in organotypic cultures of human outer root sheath cells.
4 citations
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March 1968 in “The Lancet” The study observed unexpected blue fluorescence in urine linked to salicylate metabolite presence, suggesting "aspirin addiction" in patients with unexplained hair loss, potentially tied to chronic disease or hair production interference.
March 2026 in “Journal of the American Academy of Dermatology” In this study, patients with active lymphocytic cicatricial alopecia showed significant improvement using a three-stage treatment regimen involving Tofacitinib, Apremilast, and Crisaborole, with 93.5% experiencing marked improvement and only three mild adverse events reported.
75 citations
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January 2014 in “Archiv Der Pharmazie” This review discusses the synthesis and biological activities of jasmonates, highlighting their potential as drugs and prodrugs, but reports no new clinical results; further research and trials are anticipated.
3 citations
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June 2019 in “Journal of cosmetic dermatology” In this study, tresses treated with pH 1.0 acid straightener showed better straightening but more damage to hair properties compared to those treated with pH 2.0.
3 citations
,
June 2011 in “Clinical Cosmetic and Investigational Dermatology”
October 2022 in “International journal of research and review” This case report suggests that intracanal medication with calcium hydroxide paste may alleviate colitis symptoms triggered by Formacresol used during dental retreatment in a 46-year-old patient.
4 citations
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January 2016 in “Journal of analytical & bioanalytical techniques” This study evaluated a hair growth gel with Hibiscus rosa sinensis, Eclipta alba, and Solanum nigrum extracts, demonstrating consistent homogeneity, 5 α-reductase inhibitory activity, and no skin irritation.
March 2017 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that probiotics, specifically the L. plantarum MTCC 1325 strain, may have protective effects against Alzheimer's-like symptoms induced by D-Galactose in animal models, suggesting potential therapeutic use for neurodegenerative disorders.
1 citations
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June 2023 in “The FASEB journal” This study found that in mice, LSD1 interacting with HSP90 accelerates skin wound healing by enhancing HFSC glycolytic metabolism, proliferation, and differentiation via the c-MYC/LDHA axis.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports the discovery of LX-38, a new high-affinity non-steroidal antagonist that could provide the therapeutic benefits of current BPH and AGA treatments without the hormonal side effects, utilizing a distinct "Orthogonal T-Stacking" scaffold for binding.
April 2018 in “Journal of Investigative Dermatology” This study found that women taking a daily oral supplement with omega-3 fatty acids, phytonutrients, and antioxidants for 14 weeks reported perceived improvements in hair growth, strength, and moisturization.
6 citations
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June 1976 in “Journal of ultrastructure research” This study identified the presence of recognizable organelles, such as lysosomes and mitochondria, in both the keratinized fiber and the hardened inner root sheath of the Romney wool follicle.
October 2025 in “Pharmaceutical Development and Technology” In this study, cetirizine hydrochloride was formulated into niosomal and cubosomal gels, showing potential for off-label use in treating androgenic alopecia due to effective skin permeation and acceptable safety profiles; cubosomal gels exhibited superior permeation compared to niosomal gels.
2 citations
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May 2021 in “Molecules” This study reports that the metanephrine content was significantly higher in patients with alopecia areata compared to those without the condition.
October 2021 in “QJM: An International Journal of Medicine” This study found that N-acetyl-cysteine alone or combined with minoxidil improved hair parameters in men with early-onset androgenetic alopecia, with tolerable side effects.
12 citations
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November 2014 in “Bioscience, Biotechnology, and Biochemistry” In this study, the researchers successfully increased dipicolinic acid production in Bacillus subtilis by genetically modifying the spoVF operon, achieving a significant productivity improvement in the culture medium.
This trial will compare the effectiveness of spironolactone to doxycycline for treating acne in adult females, potentially offering an alternative to antibiotics and isotretinoin.
2 citations
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April 2024 in “Science & Technology Indonesia” In this study, extracts from the bark of Albizia saponaria, particularly the ethyl acetate fraction, showed significant antioxidant activity, potentially due to its high phenolic and flavonoid content, suggesting its usefulness as a source of antioxidants for pharmaceutical formulations.
This study found that the methanolic heartwood extract of Avicennia marina significantly inhibited the enzyme 5 alpha-reductase type 1 in a cell-based assay, suggesting potential anti-androgenic effects for treating androgenic alopecia.
18 citations
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January 2022 in “TURKISH JOURNAL OF AGRICULTURE AND FORESTRY” This study examined the extracts and essential oil from Platycladus orientalis leaves and found that the ethanol extract had the highest antioxidant activity, while the essential oil was more effective as an antibacterial agent, particularly against Micrococcus luteus and Staphylococcus aureus.