Probiotics: An Adjuvant Therapy for D-Galactose Induced Alzheimer's Disease
March 2017
in “
Zenodo (CERN European Organization for Nuclear Research)
”
Studysummary This study found that probiotics, specifically the L. plantarum MTCC 1325 strain, may have protective effects against Alzheimer's-like symptoms induced by D-Galactose in animal models, suggesting potential therapeutic use for neurodegenerative disorders. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated the use of Lactic Acid Bacteria, specifically L. plantarum MTCC 1325, as an adjuvant therapy for Alzheimer's disease induced by D-Galactose, which was known to cause oxidative stress and neurodegeneration. The research showed that L. plantarum MTCC 1325 improved memory and cognitive functions in rats with Alzheimer's disease by enhancing cholinergic neurotransmission and stabilizing neuronal membranes, indicating its potential protective role against neurodegeneration. The study recommended further research on higher mammalian models to confirm these findings.
