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Chinese domestic goats have unique genetic traits due to domestication and geographic isolation.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

New findings explain how genetic changes, body clocks, and certain molecules affect tissue response to stress hormones.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Longer CAG repeat lengths in the androgen receptor gene are linked to higher testosterone levels in women with PCOS.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Certain gene variations might be linked to severe acne in women but not in men.

A genetic variant in the androgen receptor gene increases heart disease risk in women but not in men.

A new mutation linked to partial Androgen Insensitivity Syndrome and prostate cancer was found in a patient unhappy with their female gender assignment.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.