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This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.

This paper reviews the molecular mechanisms involved in hair follicle development, highlighting their potential impact on human health and well-being, and discusses advancements in treating hair loss, enhancing wound healing, and developing cosmetic treatments.

This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.

This study found that overexpressing FGF22 in dermal papilla cells enhanced hair follicle stem cell proliferation and viability, while its knockout reduced these attributes, indicating its role in hair follicle regeneration.

This study found that zebrafish with a mutation in the GDP-fucose biosynthesis gene exhibited enhanced and faster regeneration of mechanosensory hair cells, implicating the importance of this gene and Notch signalling regulation in hair cell regeneration mechanisms.

This study developed a bioengineering method to reconstruct embryonic dorsal skin from dissociated chick skin cells, allowing feather buds to form and grow in vitro, influenced by epithelial-mesenchymal interactions.

In this study, researchers found that miR-143-3p may play a novel role in cashmere growth by directly repressing the expression of Itga6 in secondary hair follicles of goats.

In this study, maslinic acid applied topically was observed to stimulate hair growth in mice comparably to minoxidil, primarily activating pathways like Wnt/β-catenin, and suggesting a link between hair growth and cilia activity.

This study identified numerous genes that change expression across the anagen, catagen, and telogen stages of cashmere goat hair follicle development, highlighting key signaling pathways involved.

This review discusses the critical role of BMP signaling in the development and regulation of skin and hair follicles and notes that further research could aid therapeutic advances; it presents no new clinical results.

This review discusses the plasticity of stem cell populations and their ability to switch between functions for tissue homeostasis and regeneration, emphasizing environmental and hormonal influences, and reports no new results.

This study discovered that a network controlled by the gene p63 is crucial for keratinocyte differentiation and is linked to MYC through cell adhesion-related pathways.

This review discusses the role of hair follicle stem cells as active signaling centers in skin homeostasis, highlighting recent advancements and reporting no new clinical results.

This study identified 12 potential candidate biomarkers associated with hair loss by analyzing the differential expression of genes, suggesting possible therapeutic targets for alopecia.

This study reports differential gene expression in the leading edge and inner surface epithelial cells of murine eyelids, suggesting that distinct signaling pathways are active during embryonic eyelid closure.

This review discusses genetically-engineered mouse models for studying melanocytes and reports no new experimental findings; it emphasizes their potential to address unanswered questions in melanoma biology.

This study reviews the regulatory mechanisms and molecular processes governing stem cell activity in hair follicles, highlighting their roles in hair regeneration and potential implications for treating hair and skin disorders.

This review discusses the niches supporting adult stem cells in various organisms, including well-studied germline niches and the less understood mammalian niches, but it reports no new research findings.

This review discusses the role of Hedgehog signaling in epidermal and hair follicle development and its involvement in basal cell carcinoma, without reporting new empirical findings.

This study found that human progenitor keratinocytes form unique complements of enhancers and super-enhancers during differentiation and migration, influencing gene expression and skin disease variant enrichment.

This review discusses the role of intermediate filaments in cell signaling and differentiation, emphasizing their impact on stem cell function, development, and disease, but reports no new clinical results.

This paper discusses the multipotency of cyst cells and proposes that understanding molecular circuits in cyst formation could enable engineering of desired stem cell culture phenotypes, but reports no new experimental outcomes.

This study constructed a ceRNA regulatory network related to cashmere goat secondary hair follicle development, highlighting the role of circRNA in their morphogenesis through the ceRNA mechanism.

This study reported that alopecia in giant pandas may be linked to abnormal expression of several hair-related genes and pathways, providing insight for potential prevention and treatment strategies.

This study analyzed circular RNA expression in the developing skin of foetal Gansu Alpine fine-wool sheep, identifying key circRNAs potentially involved in secondary follicle development through regulatory networks, providing insights for wool trait improvement.

This study found that vitamin D supplementation in diets of Rex rabbits improved hair follicle development and fatty acid metabolism, with 1400–2100 IU/kg proving most effective for hair density and 2800 IU/kg increasing hair length.

This review highlights the multifaceted roles of hair follicles in skin health, emphasizing their contribution to skin tumorigenesis, homeostasis, and wound healing, and how dysregulation in associated pathways like Wnt, Hedgehog, and Notch may contribute to skin cancer development.

In this study, researchers analyzed miRNA and gene expression in the hair follicles of FMD during different hair cycle stages, identifying differential expression patterns and key pathways involved in hair follicle development and growth.

This review highlights the therapeutic potential of hair follicle stem cells in tissue repair and hair regeneration, discussing the molecular mechanisms and the impact of natural compounds on stem cell properties, which may support the development of novel hair loss treatments.

This review discusses various gene therapy and non-viral delivery methods to promote angiogenesis for chronic wound healing, but it reports no new clinical results.