Screening of circRNAs Associated with Secondary Wool Follicle Development in Fine-Wool Sheep and Construction of Their ceRNA Network

    September 2025 in “ Animals ”
    Yu Luo, Binpeng Xi, Yufang Song … Tingting Guo
    Studysummary This study analyzed circular RNA expression in the developing skin of foetal Gansu Alpine fine-wool sheep, identifying key circRNAs potentially involved in secondary follicle development through regulatory networks, providing insights for wool trait improvement.
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    Research cited in this study 14

    1. Comprehensive Analysis of the Expression Profiles of mRNA, lncRNA, circRNA, and miRNA in Primary Hair Follicles of Coarse Sheep Fetal Skin BMC Genomics · 2024
    2. Hordenine Activated Dermal Papilla Cells and Promoted Hair Regrowth by Activating Wnt Signaling Pathway Nutrients · 2023
    3. Proteomics Analysis of the Secondary Hair Follicle Cycle in Liaoning Cashmere Goat Small ruminant research · 2021
    4. Multiple Potential Roles of Thymosin Beta 4 in the Growth and Development of Hair Follicles Journal of Cellular and Molecular Medicine · 2021
    5. CircRNA-1926 Promotes Differentiation of Goat SHF Stem Cells into Hair Follicle Lineage by miR-148a/b-3p/CDK19 Axis Animals · 2020
    6. Systematic Analysis of Non-coding RNAs Involved in the Angora Rabbit Hair Follicle Cycle by RNA Sequencing Frontiers in genetics · 2019
    7. Expression Profile Analysis of MicroRNAs During Hair Follicle Development in the Sheep Fetus Bioscience, biotechnology, and biochemistry · 2019
    8. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016
    9. Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence Cell reports · 2015
    10. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015
    11. Molecular Principles of Hair Follicle Induction and Morphogenesis BioEssays · 2005
    12. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    13. The Microanatomy, Cell Replication, and Keratin Gene Expression of Hair Follicles During a Photoperiod-Induced Growth Cycle in Sheep Cells tissues organs · 1995
    14. Hair Anatomy for the Clinician Journal of The American Academy of Dermatology · 1991

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