1 citations
,
October 2024 in “The American Journal of Gastroenterology” This case study suggests that the use of the dietary supplement Nutrafol may have led to drug-induced liver injury in a 26-year-old woman, as evidenced by increased liver enzymes and bilirubin levels which improved after stopping the supplement.
May 2004 in “International Journal of Cosmetic Science” This study found that kojic acid and niacinamide were the most effective inhibitors of UVB-induced NF-κB activation and IL-6 secretion in HaCaT keratinocytes, suggesting a role in modulating melanotrophic factor synthesis.
January 2026 in “International Journal of Health Engineering and Technology” In this study, researchers evaluated the effects of green spinach leaf extract on hair growth in New Zealand rabbits and found that the 15% concentration formula resulted in the highest average hair growth compared to other concentrations and controls.
February 2024 in “Molecules/Molecules online/Molecules annual” In this study, NMN was found to reverse hair follicle atrophy, thinning, and sparsity in mice induced by DHT, and significantly decreased DHT-induced inflammation and oxidative stress in cultured human dermal papilla cells, enhancing hair growth-related markers.
21 citations
,
April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” This study suggests that gel containing OSF3 loaded in niosomes offers high transfollicular penetration for topical anti-androgenic alopecia treatment with minimal systemic effect.
December 2021 in “Bandung Conference Series. Pharmacy” This literature review found that combinations of certain herbal extracts with coconut oil, such as Hibiscus rosa sinensis and Centella asiatica, promoted hair growth in animals over 30 days, with varied results across rat and rabbit models.
In this study, researchers developed isotretinoin-loaded Delonix polymeric nanoparticles that target hair follicles and found they effectively sustained drug release, reduced IL-6 production in vitro without inhibiting P. acnes, and may prevent isotretinoin-related skin irritation in vivo in Wistar rats.
September 2025 in “Cosmetics” In this study, oral supplementation with NMN for 12 weeks in middle-aged Japanese women significantly increased hair growth density and diameter and improved subjective assessments of hair texture and quality of life, with no significant changes in hair hormone concentrations observed.
8 citations
,
April 2022 in “Nutrients” In this study, Ishige sinicola extract was observed to improve bone density and structure in an animal model of estrogen deficiency-induced osteoporosis, suggesting its potential as a therapeutic option for postmenopausal osteoporosis by inhibiting osteoclast formation without cytotoxic effects.
1 citations
,
January 2014 in “Journal of clinical & experimental dermatology research” This study suggests that the fresh leaf extracts of Naringi crenulata may promote hair growth in Wistar rats, potentially due to the presence of terpenoids and flavonoids.
July 2018 in “Media Informasi” This study found that a 3:2 combination of pandan leaf and mother-in-law's tongue extracts in hair tonic showed similar hair growth activity as 5% minoxidil after three weeks.
3 citations
,
January 2014 This study concluded that a green tea extract hair tonic was stable, promoted more hair growth than 2.5% minoxidil, and did not cause skin irritation.
3 citations
,
October 2018 in “Revista de Chimie” This review discusses the potential medicinal properties and pharmacokinetic features of nettle compounds ursolic acid and quercetin, highlighting quercetin as a promising candidate for antioxidant and anti-aging effects, but reports no new clinical results.
1 citations
,
August 2024 in “Polymers” This study observed that dissolving microneedles made from PVP-K90 and HPMC E50, incorporating Oryza sativa L. extract complex, showed enhanced transfollicular skin penetration and maintained safety for keratinocytes, with the P25H5 formulation demonstrating faster dissolution and greater effectiveness.
January 2018 in “The journal of the convergence on culture technology” This study observed that applying astringent persimmon fruit extract may significantly enhance hair growth and lengthen the hair in genetically balding Black mice.
This study found that an herbal extract from Marking nuts, when compared to a standard drug, effectively inhibited the dandruff-causing organism Malassezia furfur and promoted hair growth on mice, suggesting potential use for dandruff treatment and hair rejuvenation.
December 2025 in “Chemical Biology & Drug Design” This study suggests that hesperidin may regulate pathways in hair follicle cells to help mitigate hair loss, revealing molecular mechanisms of nitric oxide donor-mediated hair follicle protection.
August 2014 in “Journal of clinical & experimental dermatology research” This study found that using Cerita anti hair loss tonic significantly reduced daily hair loss in men compared to a temple lotion, suggesting potential benefits of herbal stimulators in addressing androgenic hair loss.
2 citations
,
August 2016 in “Journal of Investigative Dermatology” November 2022 in “Journal of Investigative Dermatology” This study suggests that the Anetholea anisita extract improved scalp health by increasing specialized pro-resolving mediators and reducing pro-inflammatory markers, leading to decreased dandruff and enhanced hair brightness in dandruff sufferers.
February 2025 in “Journal of Pharmaceutical and Health Research” This study examined the cytotoxic effects of arumanis mango rind extract and its fractions on T47D breast cancer cells, with results showing that ethanol extract and ethyl acetate fraction exhibited significant potential in reducing cell viability, similar to the effects of doxorubicin.
1 citations
,
June 2025 in “International Journal of Plant and Environment” This study found that nickel oxide nanoparticles synthesized using Alternanthera sessilis extract may have potential as antimicrobial, antifungal, and dye-removal agents.
January 2019 in “Prosiding Program Kreativitas Mahasiswa” This study found that a 15% Pisum sativum extract concentration in hair tonic showed the most effective hair growth, with a length of 14.51mm and weight of 0.16g.
1 citations
,
June 2025 in “Biomolecules” This study found that extracts from Stauntonia hexaphylla leaves and fruits, particularly those with a higher leaf-to-fruit ratio, significantly enhanced osteogenic activity and inhibited osteoclast-related gene expression in vitro, suggesting potential for osteoporosis prevention.
This study found that adding menthol to Phyllanthus niruri ethanol extract gel enhanced hair growth and thickness in rats compared to the gel without menthol.
1 citations
,
April 2022 in “Applied sciences” This study reports the development of a microemulsion using Momordica charantia extract, which demonstrated strong antioxidant and 5α-reductase inhibitory activity, potentially aiding hair loss management. The microemulsion was stable over 12 weeks, suggesting its future potential for cosmetic or pharmacological applications.
December 2018 in “Jurnal Farmamedika (Pharmamedica Journal)” This study found that a combination of ethanol extract from watermelon white skin and liquid from kepok banana tree trunk resulted in greater hair growth length in rats compared to Minoxidil.
January 2023 in “Food and nutrition sciences” This study observed that a significant majority of participants who used the dietary supplement Nutrifii™ Renew reported improvements in various health outcomes, including sleep and energy, compared to a multivitamin/mineral group.
March 2023 in “Jurnal Ilmiah Medicamento” In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.
October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.