Synergistic Effect of Stauntonia Hexaphylla (Thunb.) Decne Fruit and Leaf on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation

    June 2025 in “ Biomolecules ”
    Reshmi Akter, Muhammad Awais, Md Niaj Morshed … Deok‐Chun Yang
    Studysummary This study found that extracts from Stauntonia hexaphylla leaves and fruits, particularly those with a higher leaf-to-fruit ratio, significantly enhanced osteogenic activity and inhibited osteoclast-related gene expression in vitro, suggesting potential for osteoporosis prevention.
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    Research cited in this study 2

    1. Comparison of Three Different Lactic Acid Bacteria-Fermented Proteins on RAW 264.7 Osteoclast and MC3T3-E1 Osteoblast Differentiation Scientific reports · 2023
    2. Stauntonia Hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-Induced Alopecia Mice Iranian Journal of Pharmaceutical Research · 2023