May 2024 in “Clinical Cosmetic and Investigational Dermatology” Manipulating cell cleanup processes could help treat hair loss.
March 2024 in “Cosmoderma” Botulinum toxin is used for neck, shoulder, calf, and ankle slimming, and hair loss treatment, but can cause muscle weakness and atrophy with regular use.
January 2024 in “SAGE Open Medical Case Reports” Minoxidil can help increase facial hair growth.
February 2023 in “Clinical, Cosmetic and Investigational Dermatology” The study involving 80 male patients with androgenetic alopecia (AGA) and 60 healthy controls found that AGA patients had significantly higher leptin levels, lower Adpn/Lep ratios, and lower vitamin D levels. Insulin resistance was more prevalent in AGA patients, but no significant differences were observed in serum adiponectin, resistin, visfatin, and insulin levels between the groups. Decreased Adpn/Lep ratio and increased serum leptin level were identified as independent risk factors for AGA. The findings suggest that adipokine imbalance and vitamin D deficiency may play roles in the pathogenesis of AGA, and that addressing these factors could be beneficial in managing the condition.
665 citations,
April 2016 in “Nature communications” Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
85 citations,
April 2012 in “PLOS ONE” Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.
79 citations,
December 2017 in “Cosmetics” The document reviewed in vitro studies on sunscreen permeation and retention, emphasizing the importance of formulation strategies to prevent systemic absorption and potential DNA damage. It discussed the effectiveness and stability of various UV filters, the impact of nanotechnology, and the use of three-dimensional human skin cultures as alternatives to animal testing. Techniques like encapsulation in lipid nanoparticles and bioadhesive nanoparticles were found to reduce skin penetration and enhance photoprotection. The review highlighted the need for standardized in vitro methods to predict in vivo performance and ensure regulatory compliance.
52 citations,
February 2012 in “PloS one” Lack of Ctip2 in skin cells delays wound healing and disrupts hair follicle stem cell markers in mice.
51 citations,
April 2020 in “Cells” Special cell particles from macrophages can help hair grow.
30 citations,
November 2015 in “Advanced Pharmaceutical Bulletin” Nanoethosomes can improve the skin penetration of Lidocaine for topical use.
12 citations,
April 2019 in “Scientific Reports” A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
9 citations,
April 2019 in “Biomolecules & Therapeutics” Udenafil may help hair grow by activating certain stem cells.
7 citations,
December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
2 citations,
January 2019 in “Journal of Cosmetics, Dermatological Sciences and Applications” The supplement and lotion significantly reduced hair loss and improved hair health.
September 2024 in “Stem Cell Research & Therapy” HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.
January 2024 in “Journal of developmental biology” Abdominal skin heals faster than dorsal skin because it has more stem cells.
December 2023 in “Azerbaijan Pharmaceutical and Pharmacotherapy J” The minoxidil gel could be a better treatment for hair loss than traditional forms.
June 2023 in “Antioxidants” Lipids from Schizochytrium sp. help prevent hair loss by protecting hair cells from damage and promoting hair growth.
July 2022 in “Journal of the Dermatology Nurses' Association” The document encourages attending the 2023 Dermatology Nurses' Association Convention.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
September 2018 in “Practical diabetes” People with diabetes have a higher risk of skin infections and complications.
February 2023 in “Frontiers in Pharmacology” Water extract of Cacumen Platycladi helps hair growth by activating specific cell pathways.
The review highlights the potential of natural products in treating hair loss by activating the Wnt/β-catenin signaling pathway, which is crucial for hair follicle development, hair cycle regulation, and hair regeneration. Traditional treatments like finasteride and minoxidil have limitations, prompting research into natural compounds such as polyphenols, which show promise in promoting hair growth with fewer side effects. Key natural products identified include extracts from Aconitie Ciliare Tuber, Centipeda minima, Ginkgo biloba, Malva verticillata, and Prunus mira, which enhance β-catenin activity and other growth factors in dermal papilla cells. These findings suggest that natural products could offer safer and effective alternatives for hair loss treatment, with future research needed to explore clinical applications and potential combinations with existing drugs.
101 citations,
March 2019 in “Cell Stem Cell” Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
99 citations,
May 2013 in “Familial cancer” People with Birt-Hogg-Dubé syndrome often have lung problems and delayed diagnosis, and better recognition of CT scan signs could improve diagnosis and management.
88 citations,
June 2019 in “Cell reports” Certain small molecules can promote hair growth by activating a cellular cleanup process called autophagy.
67 citations,
September 2001 in “American Journal Of Pathology” Inhibiting ODC can prevent UV-induced skin cancer.
63 citations,
June 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
33 citations,
October 2016 in “Photomedicine and laser surgery” Future clinical uses of Intense Pulsed Light (IPL) are likely to grow and become more effective with new advancements and combined treatments.
31 citations,
November 2020 in “International journal of molecular sciences” Adipokines affect skin health and could be targeted for treating skin diseases.