research Effect of Body Mass Index on Phenotypic Features of Polycystic Ovary Syndrome in Singapore Women: A Prospective Cross-Sectional Study
High BMI worsens hair growth in women with PCOS.
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research HMGB1 Promotes Hair Growth via the Modulation of Prostaglandin Metabolism
A protein called HMGB1 helps hair grow by affecting prostaglandin metabolism.
research Evaluation of Association of Vitamin D in Alopecia Areata: A Case-Control Study of 100 Patients in a Tertiary Rural Hospital of Southern India
People with alopecia areata often have lower vitamin D levels, which may be linked to the condition's severity.
research Selection Signatures for Fiber Production in Commercial Species: A Review
Genomic research can help improve the quality and production of natural fibers in animals.
research TRPV3 Ion Channel: From Gene to Pharmacology
The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.
research Antiandrogenic Activity of Riboflavin 5′-Phosphate (FMN) in 22Rv1 and LNCaP Human Prostate Cancer Cell Lines
Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
research Innovative Approach for Polycystic Ovary Syndrome Treatment: Brown Adipose Tissue
Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
research Melanocyte Cell States Defined and Visualized in Developing Mouse Skin
Researchers found three types of melanocytes in developing mouse skin, each with different genes and locations.
research A Case Control Study of Serum Vitamin D Levels in Alopecia Areata
People with alopecia areata had lower vitamin D levels, but these levels did not relate to how severe their condition was.
research Y27632 Promotes Proliferation via EGFR Signaling in a Newly Isolated and Characterized Human Primary Sebocyte Cell Line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
research Scarless Wound Healing: Finding the Right Cells and Signals
The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.
research TGFβ Signaling Regulates Lipogenesis in Human Sebaceous Gland Cells
TGFβ signaling prevents sebaceous gland cells from producing fats.
research Growth in Turface Clay Permits Root Hair Phenotyping Along the Entire Crown Root in Cereal Crops and Demonstrates That Root Hair Growth Can Extend Well Beyond the Root Hair Zone
Root hairs in cereal crops can grow beyond the usual zone, and using Turface® clay helps study this.
research Lgr6+ Stem Cells and Their Progeny in Mouse Epidermis Under Regimens of Exogenous Skin Carcinogenesis, and Their Absence in Ensuing Skin Tumors
UV exposure reduces Lgr6+ stem cells in mouse skin and they don't significantly contribute to skin cancer development.
research Novel Mutations of the ABCA12, KRT1 and ST14 Genes in Three Unrelated Newborns Showing Congenital Ichthyosis
New genetic mutations linked to rare skin disorders were found in three newborns.
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Thermodynamically Stable Ionic Liquid Microemulsions for Topical Delivery and Peptide Application
New method improves copper peptide delivery for hair growth three times better than current options.
research Expansion Culture of Hair Follicle Stem Cells Through Uniform Aggregation in Microwell Array Devices
The new microwell device helps grow more hair stem cells that can regenerate hair.
research Autophagy Dysfunction: The Kernel of Hair Loss?
Manipulating cell cleanup processes could help treat hair loss.
research Dandruff Lesional Scalp Skin Exhibits Epidermal T Cell Infiltration and a Weakened Hair Follicle Immune Privilege
Dandruff is linked to increased T cells and weakened immune protection in hair follicles.
research Efficacy of Derinat as a Treatment for Murine and Androgenetic Alopecia Patients
Derinat may improve hair growth and quality of life in hair loss patients by reducing oxidative stress.
research Analysis of 72,469 UK Biobank Exomes Links Rare Variants to Male-Pattern Hair Loss
Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.
research Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation
TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research A Slow-Cycling LGR5 Tumor Population Mediates Basal Cell Carcinoma Relapse After Therapy
A small group of slow-growing cells causes basal cell carcinoma to return after treatment.
research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling During Hair Follicle Stem Cell Lineage Progression
Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
research Dynamic Regulation of Retinoic Acid-Binding Proteins in Developing, Adult, and Neoplastic Skin Reveals Roles for β-Catenin and Notch Signaling
Retinoic acid-binding proteins in skin are regulated by β-catenin and Notch signalling.
research Aldo-Keto Reductase (AKR) 1C3 Inhibitors: A Patent Review
The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.
research Analyses of Regenerative Wave Patterns in Adult Hair Follicle Populations Reveal Macro-Environmental Regulation of Stem Cell Activity
Hair follicle stem cells are controlled by their surrounding environment.
research Selective Androgen Receptor Modulators Negatively Regulate Triple-Negative Breast Cancer Growth and Epithelial-Mesenchymal Stem Cell Signaling
SARMs may be an effective treatment for a certain type of breast cancer by blocking cancer growth and spread.