Derinat Extends Hair Cycle at Anagen Phase by Decreasing the Level of TRPCs-Mediated Intracellular ROS Accumulation in Skin
TLDR Derinat helps extend hair growth by reducing harmful molecules in skin cells.
The study investigated the effects of Derinat on hair growth in mice by focusing on its ability to maintain the hair cycle at the anagen phase. Derinat was applied to the dorsal skin of BALB/c nude mice and C57BL/6 mice, and it was found to restrain the hair growth pattern changes by decreasing intracellular ROS accumulation. This reduction in ROS was linked to the inhibition of TRPCs activity, which is associated with Ca2+ signaling in skin cells. The findings suggest that Derinat's efficacy as a hair restorer is due to its ability to maintain the anagen phase of the hair cycle by reducing TRPCs-mediated intracellular ROS accumulation.
