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    Did you mean NF-κB activation?
    Glossary NF-κB activation

    process where a protein complex moves to the nucleus

    NF-κB activation refers to the process by which the NF-κB (Nuclear Factor kappa-light-chain-enhancer of activated B cells) protein complex is triggered to move from the cytoplasm into the nucleus of a cell. Once in the nucleus, it binds to DNA and activates the transcription of specific genes involved in immune and inflammatory responses, cell growth, and survival. This pathway is crucial in many biological processes and is often implicated in diseases such as cancer and autoimmune disorders.

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    1. 647 NLRP1 promotes tumor growth by enhancing inflammasome activation and suppressing caspase-3 activity in human melanoma Journal of Investigative Dermatology · 2016 · 1 citations
    2. Downregulation of nuclear factor-kappaB activation in human keratinocytes by melanogenesis inhibitors International Journal of Cosmetic Science · 2004
    3. Activation of TLR3 Enhance Stemness and Immunomodulatory Properties of Periodontal Ligament Stem Cells (PDLSCs) Springer eBooks · 2016 · 3 citations
    4. Activation of nuclear factor κB in response to cream ingestion is related to ovarian androgen hypersecretion in polycystic ovary syndrome Fertility and Sterility · 2013 · 6 citations
    5. Jieduquyuziyin prescription alleviates SLE complicated by atherosclerosis via promoting cholesterol efflux and suppressing TLR9/MyD88 activation Journal of Ethnopharmacology · 2023 · 6 citations
    6. Hallmark evidence of lipopolysaccharide (LPS) tolerance in obese women with polycystic ovary syndrome (PCOS) - LPS-induced NFkB suppression in mononuclear cells (MNC) is linked to hyperandrogenism in PCOS Fertility and Sterility · 2018
    7. Genome-wide shifts in gene expression induced in theca-interstitial cells by inflammatory stimuli Fertility and Sterility · 2018
    8. Polydeoxyribonucleotide (PDRN) salmon sebagai agen anti penuaan Intisari Sains Medis · 2025
    9. Genetic deletion of TNFα inhibits ultraviolet radiation-induced development of cutaneous squamous cell carcinomas in PKCε transgenic mice via inhibition of cell survival signals Carcinogenesis · 2015 · 11 citations
    10. Involvement of DKK1 secreted from adipose‐derived stem cells in alopecia areata Cell Proliferation · 2023
    11. The influence of non-esterified fatty acids (NEFA) on the ovarian production of androgens in a context of in vitro fertilisation (IVF) – preliminary results Fertility and Sterility · 2013
    12. XEDAR activates the non-canonical NF-κB pathway Biochemical and Biophysical Research Communications · 2015 · 18 citations
    13. Down-RANKing the Threat of HSV-1: RANKL Upregulates MHC-Class-I-Restricted Anti-Viral Immunity in Herpes Simplex Virus Infection Journal of Investigative Dermatology · 2015 · 2 citations
    14. Oral administration of berberine represses macrophage activation-associated benign prostatic hyperplasia: a pivotal involvement of the NF-κB Aging · 2021 · 8 citations
    15. Biotin Supplementation Ameliorates Murine Colitis by Preventing NF-κB Activation Cellular and Molecular Gastroenterology and Hepatology · 2019 · 55 citations
    16. Hair Follicle Disruption Facilitates Pathogenesis to UVB-Induced Cutaneous Inflammation and Basal Cell Carcinoma Development in Ptch+/− Mice American Journal of Pathology · 2014 · 8 citations
    17. Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair Developmental Cell · 2013 · 52 citations
    18. Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress International Journal of Nanomedicine · 2016 · 43 citations
    19. A new mutation resulting in the truncation of the TRAF6-interacting domain of XEDAR: a possible novel cause of hypohidrotic ectodermal dysplasia: Figure 1 Journal of Medical Genetics · 2012 · 17 citations
    20. In Vivo Evaluation of<i>Eclipta alba</i>Extract as Anticancer and Multidrug Resistance Reversal Agent Nutrition and Cancer · 2014 · 9 citations
    21. Selected Abstracts Annals of Nutrition and Metabolism · 2008
    22. Gata6 promotes hair follicle progenitor cell renewal by genome maintenance during proliferation The EMBO Journal · 2016 · 29 citations
    23. Long noncoding RNA and gene expression analysis of melatonin-exposed Liaoning cashmere goat fibroblasts indicating cashmere growth Naturwissenschaften · 2018 · 12 citations
    24. Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations] Faculty of 1000 Research Ltd · 2022
    25. Cell death in the skin Apoptosis · 2009 · 120 citations
    26. The Acne-treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil in Vitro and in Vivo Research Square (Research Square) · 2021
    27. Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids Journal of tissue engineering · 2024
    28. Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately Stem Cell Research & Therapy · 2015 · 113 citations
    29. Nucleic acid-induced chemokine expression in keratinocytes: Implications for skin inflammation Repository of the Academy's Library (Library of the Hungarian Academy of Sciences) · 2025
    30. Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases 2026