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This study found that the FGF-2 mimetic SUN11602 and VEGF mimetic ONO-1301 had unique effects on skin fibroblasts and keratinocytes, indicating potential for improving wound healing.

This review discusses wound‐induced hair follicle neogenesis and its potential for developing therapies for scar formation, but reports no new clinical results.

This study found that conditioned medium from human placental cells or tissue promoted angiogenesis in HUVECs in vitro, with early-pregnancy placental cells and whole placental tissue showing more significant effects.

In this study, Mills et al. reported that inoculating human pericytes into murine wounds delayed dermal repair, revealing a need for better understanding of pericyte activity during skin injury repair.

This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.

Skin organoids can regenerate hair by forming specific cell units with certain signals.

This review discusses the role of extracellular vesicles as therapeutic agents for wound healing and highlights the need for further research into their clinical applications.

This article discusses the advances in understanding wound-induced hair follicle neogenesis (WIHN) and highlights the roles of specific signaling pathways and cellular plasticity, noting no clinical results but suggesting potential areas for further research.

In this study, researchers developed a novel method using ultrasound stimulation and a hydrogel delivery system to enhance the regenerative effects of stem cell-derived extracellular vesicles on severe skin injuries, resulting in improved healing and hair follicle regeneration in a mouse model.

Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.

This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.

This study found that extracellular factors from a specific developmental stage can promote hair follicle neogenesis in adult skin by facilitating interactions between fibroblasts and keratinocytes.

This study found that lymph vessel morphology and density in airways differed based on location and type of epithelium, with the highest density in the ciliated epithelium of the nasal passages and site-specific patterns apparent in both fetal and adult specimens.

This review discusses human hair follicle development and highlights the potential of creating human in vitro models and skin substitutes with hair follicles, reporting no new clinical results.

This report details a rare case of late-onset, bilateral nevus comedonicus on the eyelids in a 79-year-old man, discussing its clinical presentation and histopathologic features without presenting new research findings.

This review summarizes the latest progress and challenges in skin organoid research, emphasizing advancements in organoid construction, applications in disease modeling, and factors affecting tissue maturation, while noting barriers such as vascularization and neural integration that hinder clinical translation.

This research found that LSE transplantation positively affects wound healing by promoting granulation tissue growth and minimizing cosmetic defects in ischemic non-healing wounds during preclinical studies. Additionally, the proposed smoothing coefficient helps assess the degree of wound bed filling with developing tissue.

This article reviews the role of VEGF in hair follicle growth and cycle modulation but concludes that its specific molecular mechanisms in hair follicle growth remain unclear.

In this study, xenobiotic-free human multipotent adult progenitor cells were found to improve wound vascularization and healing in mice, suggesting potential applicability for clinical use in humans.

This study developed a multiscale spatial atlas of healthy skin and basal cell carcinoma, revealing a hair follicle origin for BCC and the expansion of specific cell populations such as POSTN+ fibroblasts and RGS5+ pericytes, suggesting roles in skin cancer stroma expansion and vascular remodeling.

This study found that injecting highly purified monocyto-angiotropin into hare skin induced new blood vessel formation and significantly accelerated hair growth at the injection site compared to control areas.

Reducing neutrophils or inhibiting NETs improves wound healing in sickle cell disease.

In this study, researchers found that tubular VCAM1 expression in transgenic mice and human kidney transplant biopsies precedes nephron loss and fibrosis, indicating its potential as an early biomarker for tubular fate and adverse kidney outcomes.

This study found that dermal papilla cells in human hair follicles exhibit stronger expression of VEGF mRNA and protein compared to other follicular cells, suggesting their key role in angiogenic processes related to hair growth.

This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.

In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.

This study observed that VEGF165 increases proliferation and migration but alters adhesion properties of cultured human hair follicle cells, indicating a potential role for VEGF/VEGFR-2 in hair follicle regulation beyond angiogenesis.

This review discusses the mechanisms of wound-induced hair neogenesis and its similarities with embryonic hair follicle development, but reports no new clinical results.