March 2024 in “Arquivos de Ciências da Saúde da UNIPAR” In this case report, a 34-year-old man experienced temporary hair loss after undergoing an endovascular procedure with fluoroscopy for facial arteriovenous malformation, which resolved within two months following treatment with topical Minoxidil and oral Cilostazol.
28 citations
,
May 2000 in “Proceedings of the National Academy of Sciences” This study demonstrated that the highly divergent WDSV rv-cyclin significantly stimulates eukaryotic cell proliferation, leading to hyperplastic skin lesions in transgenic mice.
21 citations
,
December 2017 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that fibroblast behavior switching between proliferation and ECM deposition is vital for dermal architecture, where cell migration is primarily important for tissue repair during wound healing.
8 citations
,
January 2022 in “Burns and trauma” This review discusses the role of extracellular vesicles from specific skin cells in wound healing, emphasizing their potential in regenerative medicine and reporting no new experimental results.
48 citations
,
March 2005 in “PubMed” This paper reviews the potential of various bioactive plant compounds, including resveratrol and curcumin, for modulating angiogenesis but presents no new clinical results.
9 citations
,
August 2025 in “Current Issues in Molecular Biology” This review discusses the role of extracellular vesicles in bone regeneration and their potential as therapeutics, highlighting challenges like standardization and safety for clinical application, but it reports no new clinical results.
3 citations
,
July 2023 in “International Journal of Biological Macromolecules” In this study, the researchers developed a hydrogel mimicking the fetal environment that significantly accelerated wound healing and hair follicle regeneration in vivo, with over 94% wound closure in 14 days, surpassing hydrogels lacking certain additives.
10 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” This review explores the cellular and molecular basis of wound-induced hair neogenesis and its relationship with aging but does not report new clinical results, highlighting areas for future research.
8 citations
,
October 2022 in “Biomedical Materials” This study found that incorporating hair follicle-primed spheroids into skin constructs showed potential for developing hair-bearing skin mimetics with follicle-forming abilities in vitro.
30 citations
,
March 2008 in “Wound Repair and Regeneration” This study found that estrogen affected cell behaviors differently in a scratch-wound assay, increasing VEGF secretion in follicular dermal papilla cells but decreasing it in wounded dermal sheath cells.
1 citations
,
December 2019 in “Canadian journal of ophthalmology” This study presents a case of a pubertal girl with type 1 diabetes who developed proliferative diabetic retinopathy shortly after diagnosis, suggesting the need for earlier screening in high-risk groups.
18 citations
,
September 2020 in “International Journal of Nanomedicine” This study found that both allogeneic and xenogeneic small extracellular vesicles from adipose tissue similarly enhanced soft tissue regeneration and wound healing in rat models, implying similar therapeutic effects across species.
1 citations
,
May 2026 in “Frontiers in Cell and Developmental Biology” This review explores the potential of neuro-driven hydrogels for skin and nerve regeneration, integrating biochemical cues and advanced technologies like AI for personalized wound healing, but notes the need for further validation and trials before clinical use.
12 citations
,
May 2013 in “International Journal of Molecular Sciences” In this study, researchers isolated multipotent stem cells from elderly human epidermis and showed that they could differentiate into neurons using TAT-VHL peptide, suggesting potential for regenerative therapies.
9 citations
,
March 2016 in “Natural Product Research” This study found that baicalin promotes human microvascular endothelial cell proliferation, while visnadin and minoxidil enhance tubulogenesis, with hesperidin uniquely increasing VEGFR-2 phosphorylation compared to other compounds tested.
7 citations
,
June 2022 in “Frontiers in Medicine” This review discusses the potential of adipose-derived stem cell extracellular vesicles (ADSC-EVs) in skin regeneration, highlighting mechanisms like inflammation and angiogenesis, but reports no new clinical results; challenges and future prospects are also considered.
4 citations
,
January 2000 in “Durham e-Theses (Durham University)” This study found that anagen skin in PVG rats showed significantly smaller wound diameters compared to telogen skin at 7 and 8 days after wounding, suggesting the importance of hair follicle dermal components in wound healing.
6 citations
,
November 2023 in “Stem Cell Reports” In this discussion, the authors highlight the murine cornea as a powerful model for stem cell research, revealing new insights into stem cell properties, differentiation flexibility, and the importance of the stem cell niche, with potential implications for understanding various tissues, diseases, and therapies.
11 citations
,
January 2019 in “Dermatologic Surgery” In this study, hair follicle transplantation into nonhealing ulcers promoted rapid wound closure, with differing scar quality and hair growth between the central and peripheral wound areas.
November 2008 in “Medical & surgical dermatology” This study reports that a prototype device may accurately measure changes in hair quantity, diameter, and density in patients with balding by assessing the cross-sectional area of hair bundles.
November 2024 in “ACS Materials Letters” This study developed a nitric oxide delivery system using PVA films and HA liposomes, which enhanced hair follicle vitality and repaired blood vessels in androgenic alopecia by promoting angiogenesis and reducing inflammation through the HIF-1 signaling pathway.
55 citations
,
April 2018 in “Advanced Healthcare Materials” This review discusses recent advances in scarless wound healing, focusing on strategies to create pro-regenerative scaffolds for repairing damaged skin, and reports no new clinical results.
2 citations
,
June 2006 in “Experimental dermatology” This article discusses the development of skin patterns during embryogenesis and postnatal life, linking them to genetic, environmental, and mathematical factors, but presents no new empirical findings.
4 citations
,
May 2012 in “Tissue Engineering and Regenerative Medicine” This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.
20 citations
,
October 2008 in “Archives of dermatological research” This study found that angiogenin is expressed in human dermal papilla cells, where it might stimulate hair growth by promoting cell proliferation and local skin angiogenesis.
6 citations
,
September 2014 in “Journal of the American Academy of Dermatology” In this report, researchers described a potential new variant of mucinous nevus, characterized by dilation of hair follicle pores and fibromucinous stroma in both the papillary and perifollicular dermis.
60 citations
,
July 2011 in “Stem Cells and Development” This review discusses recent findings on hair follicle morphogenesis and regeneration, focusing on molecular signals and stem cells, and suggests that understanding these processes may aid in developing new strategies for wound healing.
This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.
21 citations
,
October 2025 in “Advanced Materials” This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.
April 2019 in “Lincoln (University of Nebraska)” This study engineered a programmable platform using miniaturized needle arrays for drug delivery, showing improved wound healing outcomes in diabetic mice compared to standard topical treatments.