Nutraceuticals as Anti-Angiogenic Agents: Hopes and Reality

    March 2005 in “ PubMed ”
    Józef Dulak
    TLDR Some plant-based compounds might help control the growth of new blood vessels if further research confirms their effectiveness.
    The 2005 review discussed the potential of nutraceuticals, specifically bioactive plant compounds, as anti-angiogenic agents. Angiogenesis, the formation of new blood vessels, is crucial for organ development, ovulation, hair growth, and wound healing, but it also plays a significant role in diseases like cancer and atherosclerosis. Therefore, controlling angiogenesis could be a valuable therapeutic strategy. The review highlighted three plant compounds: resveratrol from red wine and grape-seed, epigallocatechin-3-gallate (EGCG) from green tea, and curcumin from Curcuma longa. These compounds were being tested for their potential clinical applications. The review suggested that other plant components, including those in local diets, might also be useful for modulating angiogenesis, provided their effectiveness is confirmed in scientifically validated trials.
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