Nutraceuticals as Anti-Angiogenic Agents: Hopes and Reality
March 2005
in “
PubMed
”
Studysummary This paper reviews the potential of various bioactive plant compounds, including resveratrol and curcumin, for modulating angiogenesis but presents no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.
The 2005 review discussed the potential of nutraceuticals, specifically bioactive plant compounds, as anti-angiogenic agents. Angiogenesis, the formation of new blood vessels, is crucial for organ development, ovulation, hair growth, and wound healing, but it also plays a significant role in diseases like cancer and atherosclerosis. Therefore, controlling angiogenesis could be a valuable therapeutic strategy. The review highlighted three plant compounds: resveratrol from red wine and grape-seed, epigallocatechin-3-gallate (EGCG) from green tea, and curcumin from Curcuma longa. These compounds were being tested for their potential clinical applications. The review suggested that other plant components, including those in local diets, might also be useful for modulating angiogenesis, provided their effectiveness is confirmed in scientifically validated trials.
