Viewpoint 4

The document discussed the formation and patterning of skin during embryonic and postnatal development, emphasizing the role of molecular signals and genetic factors. It highlighted the establishment of skin patterns, including hair follicles and glands, through interactions between the mesoderm, neural crest, and their environment. The study explored mathematical modeling of these patterns, particularly reaction-diffusion systems, and noted the potential for further research to understand the complex mechanisms behind skin patterning and its implications for dermatological conditions. It also examined the influence of geometry and size on pattern formation in animals and the application of these models in wound healing and surgical incision lines, emphasizing the importance of initial conditions and local anatomical factors in predicting healing outcomes.