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research Modeling cell–cell communication for immune systems across space and time

20 citations , November 2019 in “Current Opinion in Systems Biology”

This review discusses how recent studies use models and experiments to understand immune system signaling, but it reports no new clinical findings; the authors suggest strategies for improving these models.

research Viewpoint 4

2 citations , June 2006 in “Experimental dermatology”

This article discusses the development of skin patterns during embryogenesis and postnatal life, linking them to genetic, environmental, and mathematical factors, but presents no new empirical findings.

Feather Arrays Are Patterned by Interacting Signaling and Cell Density Waves

research Feather arrays are patterned by interacting signalling and cell density waves

133 citations , February 2019 in “PLoS Biology”

This research found that feather pattern formation in birds is regulated by a mechanochemical system involving fibroblast growth factor and bone morphogenetic protein signaling, which is altered in the flightless emu and ostrich.

research The developmental basis of fingerprint pattern formation and variation

44 citations , February 2023 in “Cell”

In this study, researchers found that human fingerprint ridges are formed through a modified hair follicle developmental process and spatial patterns influenced by specific signaling pathways.

research Hierarchical patterning modes orchestrate hair follicle morphogenesis

149 citations , July 2017 in “PLoS Biology”

This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.

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community Topical Dutasteride. Does it work?

in Finasteride/Dutasteride 13 upvotes 2 years ago

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

community Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)

16 upvotes 5 months ago

The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.

community Wtf have we been doing for the last 30 years

in Treatment 548 upvotes 1 year ago

Hair loss treatments like finasteride, minoxidil, and dutasteride work but have side effects. A permanent cure is still not available due to the complexity of hair loss and limited investment.

community If PP405 works it will be fkn impossible to buy it.

103 upvotes 10 months ago

PP405 is a potential hair loss treatment that may activate dormant hair follicles, but there are concerns about its effectiveness, cost, and side effects. Users discuss treatments like minoxidil, finasteride, and RU58841, expressing skepticism about PP405's long-term success and accessibility.

community 2 years treatment only getting worse any help

50 upvotes 1 year ago

The user has been using finasteride and minoxidil for over two years but is experiencing worsening hair loss. They are considering adding dutasteride, switching to oral minoxidil, and possibly a hair transplant, seeking advice on these options despite potential side effects.

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