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GlossaryForeign Body Reaction

body's immune response to an implanted or invasive object

A Foreign Body Reaction (FBR) is the body's immune response to a foreign object that has entered the tissue, such as a splinter, surgical implant, or even hair transplants. This reaction involves inflammation, the formation of a fibrous capsule around the object, and the recruitment of immune cells to the site in an attempt to isolate or expel the foreign material.

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research Adverse Cutaneous Reactions to Soft Tissue Fillers: A Review of the Histological Features

97 citations, May 2008 in “Journal of Cutaneous Pathology”

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

research Recurrent Pseudolymphomatous Reaction to Ear Piercing: 20-Year History

October 2023 in “Pathology”

A woman had a rare reaction to ear piercing that caused earlobe swelling, which was best treated by removing the piercing and not re-piercing.

research Giant Cells in Male Pattern Alopecia: A Histologic Marker and Pathogenetic Clue

8 citations, April 1979 in “Journal of Cutaneous Pathology”

Giant cells found in some male pattern baldness cases may help diagnose it and suggest hair is mistakenly seen as foreign by the body.

research Hair Implant Complications

3 citations, April 1981 in “PubMed”

Hair implants can cause infections, allergic reactions, itching, and scarring.

research Fiber Implantation for Pattern Baldness

15 citations, March 1981 in “Journal of The American Academy of Dermatology”

Fiber implantation for pattern baldness was largely unsuccessful with many complications and is not recommended.

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community Comprehensive Microneedling Guide

in Microneedling 295 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 1 year ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community Bald groom beaten over fake hair.

in Satire 881 upvotes 1 year ago

A bald groom was beaten by the family of the bride for wearing a wig. The conversation discusses the cultural stigma around baldness in India and the consequences of deception in arranged marriages.

community 19 Years Old, Progress pics of 7.5 months on topical fin/min and 3 months of Microneedling

in Progress Pictures 422 upvotes 1 year ago

A 19-year-old's progress after 7.5 months of using topical finasteride and minoxidil, as well as 3 months of microneedling, to treat hair loss. The user has experienced positive results from the treatment and expressed gratitude for the support they have received throughout their journey.

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