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This protocol describes using two-photon laser-scanning microscopy to study hair regeneration in live mice, offering detailed imaging capabilities for observing hair follicle stem cell behavior and manipulating cellular populations.

This study found that human hair follicle-derived mesenchymal stem cells maintained their proliferation and differentiation potential when cultured with acidic fibroblast growth factor, basic fibroblast growth factor, or epidermal growth factor.

This review discusses the regenerative processes of lizard tails, particularly focusing on the diversity in blastema development across different species, and reports no new findings.

This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.

This study demonstrated that β-catenin signaling in CD133+ dermal papilla cells enhances postnatal hair growth by accelerating the proliferation and differentiation of keratinocytes in the murine hair cycle.

This review discusses the identification and roles of different epidermal stem cell types in skin homeostasis and repair, and reports no new experimental findings.

This study found that MED1 deficiency in keratinocytes accelerates skin wound healing in young mice but delays healing in older mice, suggesting differential roles in epidermal regeneration with age.

In this study, vitiligo and alopecia areata were more common among patients with chronic graft-vs-host disease than previously reported, linked to higher NIH skin scores and greater immunosuppressive treatment.

This review discusses the roles of the transcription factor SOX9 in organ development and maintenance, providing insights into its regulation and diverse functions, but reports no new experimental results.

This study found that TGF-β1 expression in follicular tumors correlates with differentiation degree and suggests its potential role alongside p63 in differentiating between sebaceous and follicular tumors.

This review examines the complex mechanisms that regulate skin stem cell development, activation, and differentiation, emphasizing the molecular signaling pathways that influence their fate and contribute to skin homeostasis.

This study found that calcium microcapsules exhibited better biocompatibility and cell viability than barium microcapsules for scaffolding in artificial dermal papilla, suggesting potential for developing new hair follicle structures.

This study reported that in a mouse model, Negative Pressure Wound Therapy promotes wound healing by modulating inflammatory responses and increasing dickkopf-related protein 1, which encourages the differentiation of Hair Follicle Stem Cells into epidermal cells.

In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.

This review discusses recent advances in hair regeneration strategies, including mechanical stimulation and complementary therapies like MSC transplantation and platelet-rich plasma, and reports no new clinical results.

This review concludes that low-level laser therapy is the most supported physical treatment for androgenetic alopecia, but other therapies like nonablative laser treatments and combinations including PEMF may also be promising.

This study demonstrated that cultured epidermal stem cells and skin-derived precursors can regenerate functional hair follicles and sebaceous glands in both mice and adult humans, suggesting potential for bioengineered skin substitutes.

In this study, using stirred-suspension bioreactors to expand dermal stem cells resulted in larger numbers, but had reduced efficiency in forming hair follicle structures compared to static culture conditions.

This study found that CTHRC1 is crucial for sweat gland function and vascular network integrity in mice, and its administration improved sweat gland performance by reconstructing nearby blood vessels.

This article reviews antibody drug conjugates for cancer treatment, describing their mechanism, recent approvals, and ongoing research efforts, but reports no new clinical results.

This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.

This study found that whisker follicle stem cells transplanted to injured spinal cords in mice contributed to healing and unexpectedly grew hair at the injury site.

This study demonstrates that SDF-1/CXCL12 and CXCR4 signaling play a crucial role in directing the migration and positioning of melanoblasts in mouse hair follicle formation.

This review discusses the potential of hair follicle stem cells as a novel source for cell therapy in neurodegenerative disorders, but it reports no new clinical results.

In this study, cryopreserved mouse whisker hair follicles were shown to maintain their hair growth potential and functional recovery, with DMSO being more effective than glycerol for cryopreservation.

This study found that Sox9 was variably expressed in most canine skin neoplasms, particularly in those originating from the hair follicle's bulge region, suggesting its potential as a stem cell marker.

In this review, researchers found that TNF-α, IL-17, and JAK inhibitors show the most promise for stabilizing and resolving scarring alopecias, with IL-23 and Interferon Alpha Receptor 1 inhibitors also providing some benefits in managing these hair loss conditions.