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Phospholipid-coated nanoparticles penetrate hair follicles better than others, especially in pig ears.

This study found that porcine ear skin is more suitable than excised human skin for investigating the efficacy of barrier emulsions in preventing pollen allergen penetration due to its lack of tissue contraction.

In this study, curcumin was efficiently loaded into PS–PAA nanoparticles at the formation stage, showing even distribution at low concentrations and good biocompatibility with human skin fibroblasts.

This study found that finasteride- and minoxidil-loaded nanoparticles in a gel improved skin permeability and drug retention, suggesting a promising approach for topical alopecia treatment with reduced dosing frequency and side effects.

This review discusses the potential of follicular drug delivery systems to target the pilosebaceous unit and reports no new research findings.

This study found that a lipid-based nanoparticle formulation with oleic acid for delivering dutasteride showed lower skin permeation compared to a formulation without oleic acid, indicating its potential for targeted dermal delivery.

This review discusses how nanotechnology can enhance the efficacy of hair care products by improving the delivery and benefits of active substances and offers insights into potential risks.

This review highlights the hair follicle's structural and functional properties as an effective route for delivering active compounds in treating hair disorders, focusing on emerging carrier technologies to enhance targeted transfollicular delivery.

This study reported that newly developed minoxidil Pickering emulsion gels, designed using cellulose stabilizers, showed promising results for promoting hair regrowth and targeting hair follicles by enhancing the delivery and stabilization properties of the formulation in a hair loss treatment context.

PMS nanoparticles improve damaged hair by protecting and restoring its surface and color.

This study found that quercetin-loaded solid lipid nanoparticles demonstrated positive protective effects on human hair against UV-B light, as they controlled microscopic surface roughness, reduced chemical changes, and minimized protein loss in vitro compared to other treatments.

This article reviews various strategies, primarily developed by the Turin University Pharmaceutical Technology group, for increasing entrapment efficiency of hydrophilic molecules in nanoparticulate systems and reports no clinical results.

This study found that nanostructured lipid carriers enhanced the skin penetration and retention of minoxidil compared to solid lipid nanoparticles, suggesting they could be a promising method for topical delivery.

This review summarizes the promising role of melatonin combined with nanosized carriers in drug delivery, suggesting enhanced effectiveness in treating various diseases compared to free melatonin.

This review explores nano-quercetin formulations to enhance the solubility, stability, and targeted delivery of quercetin, highlighting its potential efficacy in treating cancer, inflammation, metabolic diseases, and tissue regeneration, though challenges in biocompatibility, toxicity, and production remain, per this source.

This chapter reviews the challenges and future prospects of using nanotechnology and phytochemistry in developing safe, effective, and precision-based therapies for Polycystic Ovary Syndrome, without reporting new clinical findings.

This review explores the potential of metal nanoparticles as innovative treatments for alopecia, highlighting their effectiveness in promoting hair regrowth, enhancing drug delivery, and modulating gene expression while also assessing the related experimental methodologies and regulatory considerations.

This review examines the advances in nanostructured lipid carriers for treating hyperpigmentation but presents no new clinical results; the authors highlight their potential benefits and applications.

This study found that nanoparticles containing minoxidil and betamethasone improved drug delivery to hair follicles, with lipidic nanoparticles significantly enhancing minoxidil and betamethasone penetration compared to control, making them a promising option for alopecia areata treatment with reduced side effects.

This review discusses technological advances in liposome systems for drug delivery and reports no new clinical results; it highlights the clinical acceptance and market presence of liposomal products.

This study found that a nanoparticle-in-nanofiber system significantly accelerated wound healing in rats by promoting angiogenesis and tissue regeneration more effectively than a commercial wound dressing.

This review examines the roles and benefits of chitosan in cosmetics and oral hygiene, highlighting its potential in the cosmeceutical market, but it reports no new results.

This research reported that squarticles, nanoparticles made from sebum-derived lipids, enhanced the follicular delivery and skin accumulation of diphencyprone and minoxidil, indicating effective drug deposition with reduced systemic absorption in alopecia treatment.

This study reviews recent advancements in microneedles made from PLGA, highlighting their use in delivering vaccines, drugs, and proteins through the skin with minimal invasiveness, and discusses the challenges and future potential of these delivery systems.

This article explains the preparation methods and applications for various vesicle and particle systems used in transdermal drug delivery, highlighting their effectiveness and potential for further development in this field.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.

This study demonstrated that using PLGA nanoparticles to deliver chlorogenic acid significantly increased type 17 collagen production in human epidermal cells, indicating potential for improved skincare formulations.

This study found that chitosan nanoparticles containing Cordyceps militaris effectively reduced lung damage in mice exposed to fine particulate matter (PM2.5) by decreasing oxidative stress and preserving lung barrier integrity, suggesting potential as a therapeutic candidate for PM2.5-induced lung diseases.

This study demonstrated that human hair can be coated with Fe3O4 nanoparticles, allowing it to be oriented and moved by a magnetic field, which may enhance drug delivery and hair care applications.